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      A Comprehensive Review of Glucose Biosensors Based on Nanostructured Metal-Oxides

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          Abstract

          Nanotechnology has opened new and exhilarating opportunities for exploring glucose biosensing applications of the newly prepared nanostructured materials. Nanostructured metal-oxides have been extensively explored to develop biosensors with high sensitivity, fast response times, and stability for the determination of glucose by electrochemical oxidation. This article concentrates mainly on the development of different nanostructured metal-oxide [such as ZnO, Cu(I)/(II) oxides, MnO 2, TiO 2, CeO 2, SiO 2, ZrO 2, and other metal-oxides] based glucose biosensors. Additionally, we devote our attention to the operating principles ( i.e., potentiometric, amperometric, impedimetric and conductometric) of these nanostructured metal-oxide based glucose sensors. Finally, this review concludes with a personal prospective and some challenges of these nanoscaled sensors.

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          Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.

          Sarah Wild, Gojka Roglic, Anders Green … (2004)
          The goal of this study was to estimate the prevalence of diabetes and the number of people of all ages with diabetes for years 2000 and 2030. Data on diabetes prevalence by age and sex from a limited number of countries were extrapolated to all 191 World Health Organization member states and applied to United Nations' population estimates for 2000 and 2030. Urban and rural populations were considered separately for developing countries. The prevalence of diabetes for all age-groups worldwide was estimated to be 2.8% in 2000 and 4.4% in 2030. The total number of people with diabetes is projected to rise from 171 million in 2000 to 366 million in 2030. The prevalence of diabetes is higher in men than women, but there are more women with diabetes than men. The urban population in developing countries is projected to double between 2000 and 2030. The most important demographic change to diabetes prevalence across the world appears to be the increase in the proportion of people >65 years of age. These findings indicate that the "diabetes epidemic" will continue even if levels of obesity remain constant. Given the increasing prevalence of obesity, it is likely that these figures provide an underestimate of future diabetes prevalence.
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            Electrode systems for continuous monitoring in cardiovascular surgery.

            Leland Clark, Champ Lyons (1962)
            Article 0 comments Cited 515 times – based on 0 reviews     Review now
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              Electrochemical glucose sensors and their applications in diabetes management.

              Adam Heller, Ben Feldman (2008)
              Article 0 comments Cited 303 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Sensors (Basel)
                Title: Sensors (Basel, Switzerland)
                Publisher: Molecular Diversity Preservation International (MDPI)
                ISSN (Electronic): 1424-8220
                Publication date Collection: 2010
                Publication date (Electronic): 12 May 2010
                Volume: 10
                Issue: 5
                Pages: 4855-4886
                Affiliations
                [1 ] Department of Advanced Technology Fusion, Konkuk University, Seoul 143-701, Korea; E-Mails: mahbub@ 123456konkuk.ac.kr (M.M.R.); saleh203@ 123456konkuk.ac.kr (A.J.S.A.)
                [2 ] KFnSC Center, Konkuk University, Seoul 143-701, Korea; E-Mail: jhjin@ 123456konkuk.ac.kr
                [3 ] Korea Research Institute of Standard and Science, Yuseong, Daejeon 305-340, Korea; E-Mail: sjahn@ 123456kriss.re.kr
                [4 ] Department of Applied Chemistry, Konkuk University, Chungju 380-701, Korea
                Author notes
                [* ] Author to whom correspondence should be addressed; E-Mail: jjlee@ 123456kku.ac.kr ; Tel.: +82-43-840-3580; Fax: +82-43-851-4169.
                Article
                Publisher ID: sensors-10-04855
                DOI: 10.3390/s100504855
                PMC ID: 3292151
                PubMed ID: 22399911
                SO-VID: f2ea47eb-fc6e-4421-9a2d-c18d53d9e3cf
                Copyright © © 2010 by the authors; licensee MDPI, Basel, Switzerland.
                License:

                This article is an Open Access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/3.0/).

                History
                Date received : 11 March 2010
                Date revision received : 7 April 2010
                Date accepted : 15 April 2010
                Categories
                Subject: Review

                ScienceOpen disciplines: Biomedical engineering
                Keywords: glucose biosensor,nanostructured metal-oxides,electrochemical principles,enzymatic sensor,nonenzymatic sensor
                Data availability:
                ScienceOpen disciplines: Biomedical engineering
                Keywords: glucose biosensor, nanostructured metal-oxides, electrochemical principles, enzymatic sensor, nonenzymatic sensor

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