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      Early Puberty in Adopted Children

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          Early puberty is frequently observed in adopted children. In various studies, early puberty has been associated with decreased final height. In Europe, studies were undertaken to treat early puberty in adopted children with GnRH agonist. This article reviews the current understanding of early puberty in adopted children, including prevalence, background and treatment options. Data from the European studies are briefly described. Besides auxological aspects, psychological items are addressed as well. Studies on the psychological effect of early puberty in adopted children are reported. Future issues include further study in the mechanism of early puberty in adopted children, evaluation of final height results of the growth studies and quality of life assessments in this specific group of children.

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          Most cited references 13

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          Secondary Sexual Characteristics and Menses in Young Girls Seen in Office Practice: A Study from the Pediatric Research in Office Settings Network

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            Neurobiological Mechanisms of the Onset of Puberty in Primates

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              Reexamination of the Age Limit for Defining When Puberty Is Precocious in Girls in the United States: Implications for Evaluation and Treatment


                Author and article information

                Horm Res Paediatr
                Hormone Research in Paediatrics
                S. Karger AG
                29 April 2002
                : 57
                : 1-2
                : 1-9
                aErasmus University Medical Centre/Sophia Children’s Hospital (Subdivision Endocrinology), Rotterdam, and bDepartment of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands
                57939 Horm Res 2002;57:1–9
                © 2002 S. Karger AG, Basel

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                Page count
                Tables: 2, References: 100, Pages: 9


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