Screening of the Filamin C Gene in a Large Cohort of Hypertrophic Cardiomyopathy Patients.

Abstract

Recent exome sequencing studies identified filamin C (FLNC) as a candidate gene for hypertrophic cardiomyopathy (HCM). Our aim was to determine the rate of FLNC candidate variants in a large cohort of HCM patients who were also sequenced for the main sarcomere genes.

Journal

Journal ID (iso-abbrev): Circ Cardiovasc Genet

Title: Circulation. Cardiovascular genetics

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1942-3268

ISSN (Print): 1942-3268

Publication date (Electronic): Apr 2017

Volume: 10

Issue: 2

Affiliations

[1 ] From the Unidad de Referencia de Cardiopatías Familiares-HUCA, Genética Molecular y Cardiología, Hospital Universitario Central Asturias, Oviedo, Spain (J.G., R.L., J.R.R., C.M., M.M., B.A., S.I., V.A., B.D.-M., P.A., E.C.); Fundación Asturcor, Spain (J.R.R., C.M.); Departamento de Medicina, Universidad de Oviedo, Spain (C.M., E.C.); Centro Salud El Cristo, Oviedo, Spain (S.T.); and Red de Investigación Renal (REDINREN), Madrid, Spain (E.C.).

[2 ] From the Unidad de Referencia de Cardiopatías Familiares-HUCA, Genética Molecular y Cardiología, Hospital Universitario Central Asturias, Oviedo, Spain (J.G., R.L., J.R.R., C.M., M.M., B.A., S.I., V.A., B.D.-M., P.A., E.C.); Fundación Asturcor, Spain (J.R.R., C.M.); Departamento de Medicina, Universidad de Oviedo, Spain (C.M., E.C.); Centro Salud El Cristo, Oviedo, Spain (S.T.); and Red de Investigación Renal (REDINREN), Madrid, Spain (E.C.). [e-mail].

Article

Publisher Item ID: CIRCGENETICS.116.001584

DOI: 10.1161/CIRCGENETICS.116.001584

PubMed ID: 28356264