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      Pharmacokinetic Modeling and Biodistribution Estimation Through the Molecular Communication Paradigm

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          Gold nanorods: their potential for photothermal therapeutics and drug delivery, tempered by the complexity of their biological interactions.

          Gold nanorods have promising applications in the fields of drug delivery and photothermal therapy. These promises arise from the nanorods' unique optical and photothermal properties, the availability of synthetic protocols that can tune the size and shape of the particles, the ability to modify the surface and conjugate drugs/molecules to the nanorods, and the relative biocompatibility of gold nanorods. In this review, current progress in using gold nanorods as phototherapeutic agents and as drug delivery vehicles is summarized. Issues of dosage, toxicity and biological interactions at three levels (biological media alone; cells; whole organisms) are discussed, concluding with recommendations for future work in this area. Copyright © 2011 Elsevier B.V. All rights reserved.
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            Nanostructure-mediated drug delivery.

            G. Hughes (2005)
            Nanotechnology is expected to have an impact on all industries including semiconductors, manufacturing, and biotechnology. Tools that provide the capability to characterize and manipulate materials at the nanoscale level further elucidate nanoscale phenomena and equip researchers and developers with the ability to fabricate novel materials and structures. One of the most promising societal impacts of nanotechnology is in the area of nanomedicine. Personalized health care, rational drug design, and targeted drug delivery are some of the benefits of a nanomedicine-based approach to therapy. This review will focus on the development of nanoscale drug delivery mechanisms. Nanostructured drug carriers allow for the delivery of not only small-molecule drugs but also the delivery of nucleic acids and proteins. Delivery of these molecules to specific areas within the body can be achieved, which will reduce systemic side effects and allow for more efficient use of the drug.
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              The internet of Bio-Nano things

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                Author and article information

                Journal
                IEEE Transactions on Biomedical Engineering
                IEEE Trans. Biomed. Eng.
                Institute of Electrical and Electronics Engineers (IEEE)
                0018-9294
                1558-2531
                October 2015
                October 2015
                : 62
                : 10
                : 2410-2420
                Article
                10.1109/TBME.2015.2430011
                f3ce5d2e-1e92-4ff2-a9dc-bde89ad30c1b
                © 2015
                History

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