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      Clinical and morphological study of calf enlargement following S-1 radiculopathy Translated title: Estudo clínico e morfológico da hipertrofia de panturrilha no curso de radiculopatia S

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          Abstract

          Calf enlargement following sciatica is a rare condition. It is reported the case of a 28-year-old woman who complained of repeated episodes of lower back pain radiating into the left buttock and foot. One year after the beginning of her symptoms, she noticed enlargement of her left calf. X-ray studies disclosed L5-S1 disk degeneration. EMG showed muscle denervation with normal motor conduction velocity. Open biopsies of the gastrocnemius muscles were performed. The left gastrocnemius muscle showed hypertrophic type 2 fibers in comparison with the right gastrocnemius. Electron microscopy showed mildly increased number of mitochondria in these fibers. A satisfactory explanation for denervation hypertrophy has yet to be provided.

          Translated abstract

          A hipertrofia da panturrilha no curso de ciática é raramente observada. É relatado o caso de uma paciente com 28 anos de idade que apresentou episódios repetidos de dor lombar irradiada para nádega e pé esquerdos. Um ano após o início dos sintomas, notou aumento da panturrilha esquerda. Estudos radiográficos revelaram degeneração do disco de L5-S1 . O exame eletromiográfico mostrou desnervação muscular com velocidade de condução motora normal. Foram realizadas biópsias dos músculos gastrocnêmios. No esquerdo notou-se hipertrofia das fibras tipo 2, em comparação ao gastrocnêmio direito. A microscopia eletrônica revelou aumento do número de mitocôndrias nas fibras hipertrofiadas. Explicação satisfatória para a hipertrofia muscular na vigência de desnervação ainda não foi definida.

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          Most cited references16

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          Myokymia muscle hypertrophy and percussion "myotonia" in chronic recurrent polyneuropathy

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            ANTERIOR-HORN CELL DEGENERATION AND GROSS CALF HYPERTROPHY WITH ADOLESCENT ONSET

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              • Record: found
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              • Article: not found

              Muscular Hypertrophy After Chronic Radiculopathy

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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                anp
                Arquivos de Neuro-Psiquiatria
                Arq. Neuro-Psiquiatr.
                Academia Brasileira de Neurologia - ABNEURO (São Paulo )
                1678-4227
                September 1992
                : 50
                : 3
                : 383-386
                Affiliations
                [1 ] Departments of Clinical Medicine
                [2 ] Universidade Federal Fluminense Brazil
                Article
                S0004-282X1992000300021
                10.1590/S0004-282X1992000300021
                f3cfedce-34bd-42b9-adec-18f5e506b87f

                http://creativecommons.org/licenses/by/4.0/

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                SciELO Brazil

                Self URI (journal page): http://www.scielo.br/scielo.php?script=sci_serial&pid=0004-282X&lng=en
                Categories
                NEUROSCIENCES
                PSYCHIATRY

                Neurosciences,Clinical Psychology & Psychiatry
                Muscle hypertrophy,calf enlargement,radiculopathy,muscular biopsy,electron microscopy,hipertrofia muscular,aumento da panturrilha,radiculopatia,microscopia eletrônica

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