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      The Nitroglycerin Exercise Test

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          Abstract

          The nitroglycerin (NTG) exercise test can help in detecting ischemia in the presence of right bundle branch block ( RBBB), left bundle branch block ( LBBB), or digitalis-induced exercise ST changes and in excluding ischemia when a falsely positive test is suspected. This treadmill test has 3-min stages at 10% grade starting at 1.5 mph and progressing in 0.5 mph increments until ST depression is observed. NTG is then given as exercise continues at the ischemia-provoking work load for up to 10 min. Among 3 patients with RBBB, 5 with LBBB, 1 on digitalis and 2 with presumed falsely positive tests, those whose ST depression lessened after NTG had ischemic thallium exercise scans; those with no change in ST depression after NTG had normal thallium images. Additional studies are needed to verify the consistency of these findings among a larger group of patients.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          978-3-8055-3437-6
          978-3-318-00026-9
          0008-6312
          1421-9751
          1981
          1981
          07 November 2008
          : 68
          : Suppl 2
          : 169-177
          Affiliations
          Exercise Laboratory-Cardiac Rehabilitation, Division of Cardiology, Montefiore Hospital and Medical Center, Albert Einstein College of Medicine, New York, USA
          Article
          173333 Cardiology 1981;68:169–177
          10.1159/000173333
          6797735
          f3d15790-ff42-42a0-98c6-6f0007c62f11
          © 1981 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 9
          Categories
          Drug Effect

          General medicine,Neurology,Cardiovascular Medicine,Internal medicine,Nephrology
          Exercise testing,Falsely positive exercise test,Treadmill protocol,Nitroglycerin,Left bundle branch block,Right bundle branch block,Digitalis,Thallium imaging

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