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      Noninvasive Adenocarcinoma in Brunner’s Gland Hyperplasia Occurring in the Third Portion of the Duodenum

      case-report

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          Abstract

          This report presents a rare case of noninvasive adenocarcinoma, which occurred in Brunner’s gland hyperplasia in the third portion of the duodenum after an 8-year follow-up. The patient’s vague symptoms were not directly related to the tumor, and the stool was negative for occult blood. Histologically, incipient carcinoma was surrounded by hyperplastic Brunner’s glands. Lysozyme and Leu 7 were uniformly positive, while chromogranin A was negative in the adenocarcinoma. Immunohistochemical study is useful in characterizing the rare case of noninvasive adenocarcinoma associated with Brunner’s gland hyperplasia.

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          Author and article information

          Journal
          DSU
          Dig Surg
          10.1159/issn.0253-4886
          Digestive Surgery
          S. Karger AG
          0253-4886
          1421-9883
          1993
          1993
          05 November 2008
          : 10
          : 4
          : 198-202
          Affiliations
          Departments of aSurgery, bInternal Medicine, cRadiology and dPathology, Kure National Hospital, Hiroshima, Japan
          Article
          172174 Dig Surg 1993;10:198–202
          10.1159/000172174
          f3d1e6c8-4ec8-4f3a-8ea4-e1e9ec96d3aa
          © 1993 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 24 May 1993
          : 04 October 1993
          Page count
          Pages: 5
          Categories
          Case Report

          Oncology & Radiotherapy,Gastroenterology & Hepatology,Surgery,Nutrition & Dietetics,Internal medicine
          Brunner’s gland,Carcinoma, noninvasive,Hyperplasia

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