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      Significant responses to platinum-based chemotherapy in renal medullary carcinoma.

      Pediatric Blood & Cancer
      Adolescent, African Americans, Anemia, Sickle Cell, complications, Antineoplastic Combined Chemotherapy Protocols, therapeutic use, Carboplatin, administration & dosage, Carcinoma, Renal Cell, drug therapy, Cisplatin, Deoxycytidine, analogs & derivatives, Female, Humans, Kidney Medulla, Kidney Neoplasms, Male, Paclitaxel, Treatment Outcome

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          Abstract

          Most patients with renal medullary carcinoma (RMC) have advanced disease at presentation and rarely respond to radiation or chemotherapy. We describe two adolescents with metastatic disease who had significant responses to cisplatin or carboplatin in combination with gemcitabine and paclitaxel.

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