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      International Journal of Nanomedicine (submit here)

      This international, peer-reviewed Open Access journal by Dove Medical Press focuses on the application of nanotechnology in diagnostics, therapeutics, and drug delivery systems throughout the biomedical field. Sign up for email alerts here.

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      Biocompatibility and applications of carbon nanotubes in medical nanorobots

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          Abstract

          The set of nanoelectromechanical systems (NEMS) based on relative motion of carbon nanotubes walls is proposed for use in medical nanorobots. This set includes electromechanical nanothermometer, jet nanoengine, nanosyringe (the last can be used simultaneously as nanoprobe for individual biological molecules and drug nanodeliver). Principal schemes of these NEMS are considered. Operational characteristics of nanothermometer are analyzed. The possible methods of these NEMS actuation are considered. The present-day progress in nanotechnology techniques which are necessary for assembling of NEMS under consideration is discussed. Biocompatibility of carbon nanotubes is analyzed in connection with perspectives of their application in nanomedicine.

          Most cited references211

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          Helical microtubules of graphitic carbon

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            Electronic structure of chiral graphene tubules

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              Carbon nanotube actuators

              Electromechanical actuators based on sheets of single-walled carbon nanotubes were shown to generate higher stresses than natural muscle and higher strains than high-modulus ferroelectrics. Like natural muscles, the macroscopic actuators are assemblies of billions of individual nanoscale actuators. The actuation mechanism (quantum chemical-based expansion due to electrochemical double-layer charging) does not require ion intercalation, which limits the life and rate of faradaic conducting polymer actuators. Unlike conventional ferroelectric actuators, low operating voltages of a few volts generate large actuator strains. Predictions based on measurements suggest that actuators using optimized nanotube sheets may eventually provide substantially higher work densities per cycle than any previously known technology.
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                Author and article information

                Journal
                Int J Nanomedicine
                International Journal of Nanomedicine
                International Journal of Nanomedicine
                Dove Medical Press
                1176-9114
                1178-2013
                September 2007
                September 2007
                : 2
                : 3
                : 361-372
                Affiliations
                [1 ]Institute of Spectroscopy, Troitsk, Moscow region, 142190, Russia;
                [2 ]Dept. of Experimental Medicine, University La Sapienza-CNR, Rome, Italy;
                [3 ]Laboratoire des Colloides,Verres et Nanomateriaux, University of Montpellier II-CNRS, Montpellier, France;
                [4 ]Laboratory for Innovation and Analysis of Bioperformances (LIAB), Biomedical Engineering Institute, Ecole Polytechnique de Montreal, Canada
                Author notes
                Correspondence: Yurii E Lozovik, Institute of Spectroscopy, Troitsk, Moscow region, 142190, Russia, Tel +7 495 334 0881, Fax +7 495 334 0886, Email lozovik@ 123456isan.troitsk.ru
                Article
                ijn-2-361
                2676659
                18019835
                f4aa3c61-e0fb-4d52-9080-4c304f9ac54c
                © 2007 Dove Medical Press Limited. All rights reserved
                History
                Categories
                Review

                Molecular medicine
                nanorobot,nanotube,biocompatibility,nanothermometer,nems
                Molecular medicine
                nanorobot, nanotube, biocompatibility, nanothermometer, nems

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