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      Distribution patterns of the contents of five biologically activate ingredients in the root of Scutellaria baicalensis

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          As an important herbaceous plant, Scutellaria baicalensis Georgi (Chinese skullcap) is geographically widespread and commonly used throughout the world. In the Chinese medicine market, S. baicalensis has been divided into two primary types, “ Ku Qin” (WXR) and “ Tiao Qin” (TST). Moreover, TST is also divided into different grades according to the diameter of roots. To explore the distribution patterns of the contents of five biologically activate ingredients (FBAI), we used six-year-old cultivated S. baicalensis and analyzed its growth characteristics as well as the quality difference among different types and diameters in roots. Throughout the entire root, we discovered that contents of the FBAI all initially increased and subsequently decreased from the top to the bottom of the roots. The baicalin content of WXR was less than that of TST. On the contrary, the contents of baicalein, wogonin, and oroxylin A in WXR were up to about two times higher than that in TST. We also found that the 0 to 40 cm part of the S. baicalensis root possessed about 87% of the root biomass and about 92% of the contents of the active ingredients.

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          Author and article information

          Chinese Journal of Natural Medicines
          20 February 2017
          : 15
          : 2
          : 152-160
          1School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China
          2Chengde Pharmaceutical Co., Ltd Affiliated to China National Group Corp. of Traditional & Herbal Medicine, Chengde 067000, China
          3National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China
          Author notes
          *Corresponding authors: WANG Wen-Quan, E-mail: wqwang@ 123456implad.ac.cn ; WEI Sheng-Li, wsl7491@ 123456126.com

          These authors have no conflict of interest to declare.

          Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.
          Funded by: National Sci-tech Support Plan
          Award ID: 2011BAI07B04 537/03430
          Funded by: Beijing Municipal Agriculture Demonstration Project
          Award ID: 20120615
          This work was supported by the National Sci-tech Support Plan (No. 2011BAI07B04 537/03430) and the Beijing Municipal Agriculture Demonstration Project (No. 20120615).


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