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      Paraproteinemia in Normal Family Members of Eight Cases with Primary Intestinal Lymphomas in Iraq

      research-article
      Oncology
      S. Karger AG
      Intestinal lymphoma, Alpha-chain disease, Paraproteinemia, Immunoelectrophoresis

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          Abstract

          Normal family members of eight patients with paraproteinemia of the primary intestinal lymphoma, had been investigated by Immunoelectrophoresis, for IgA heavy chain pattern. IgA heavy chain pattern was demonstrated in four families only, of different members, but all are of the first degree relationship. Detailed clinical, laboratory, radiological and histopathological findings of those eight cases were suggestive of malabsorption. Out of the 129 normal family members of the 8 cases, 23 cases (17.8%) had abnormal immunoglobulin in their sera. These results may explain a hereditary factor which is responsible for production of alpha-chain diseases. Supports for this hypothesis need further research.

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          Author and article information

          Journal
          OCL
          Oncology
          10.1159/issn.0030-2414
          Oncology
          S. Karger AG
          0030-2414
          1423-0232
          1978
          1978
          09 June 2009
          : 35
          : 2
          : 68-72
          Affiliations
          Albaath Specific Protein Reference Unit, Baghdad
          Article
          225258 Oncology 1978;35:68–72
          10.1159/000225258
          418369
          f5319a7e-59b0-4146-af6c-20d325363add
          © 1978 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 5
          Categories
          Paper

          Oncology & Radiotherapy,Pathology,Surgery,Obstetrics & Gynecology,Pharmacology & Pharmaceutical medicine,Hematology
          Paraproteinemia,Intestinal lymphoma,Alpha-chain disease,Immunoelectrophoresis

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