7
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Combinatorial control of Th17 and Th1 cell functions by genetic variations in genes associated with the interleukin-23 signaling pathway in spondyloarthritis.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Recent genome-wide association studies have revealed numerous genetic associations between specific single-nucleotide polymorphisms (SNPs) and immune-mediated inflammatory diseases. The current challenge is to identify associations of the genetic variants with effector mechanisms implicated in pathogenesis. This study was undertaken to investigate the link between genetic variation at loci associated with spondyloarthritis (SpA) and the effector function of CD4+ T lymphocyte subsets involved in chronic inflammatory disease.

          Related collections

          Author and article information

          Journal
          Arthritis Rheum.
          Arthritis and rheumatism
          Wiley-Blackwell
          1529-0131
          0004-3591
          Jun 2013
          : 65
          : 6
          Affiliations
          [1 ] Institut Pasteur and CNRS URA 1961, Paris, France.
          Article
          10.1002/art.37936
          23508476
          f53f8a70-345b-41a6-b2a2-c355fce11ff8
          History

          Comments

          Comment on this article