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      Primary Squamous Cell Carcinoma of the Remnant Stomach after Subtotal Gastrectomy

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          Abstract

          Primary squamous cell carcinoma (SCC) of the stomach is a very rare disease. However, the pathogenesis, clinical characteristics, and prognosis of gastric SCC are controversial and remain to be elucidated. Herein, we report a case of primary gastric SCC of the remnant stomach after subtotal gastrectomy. A 65-year-old man was admitted to our hospital due to epigastric discomfort and dizziness. He had undergone subtotal gastrectomy 40 years previously for gastric ulcer perforation. Endoscopy revealed a normal esophagus and a large mass in the remnant stomach. Abdominal computed tomography revealed enhanced wall thickening of the anastomotic site and suspected metachronous gastric cancer. Endoscopic biopsy revealed SCC. Total gastrectomy was performed with Roux-en-Y esophagojejunostomy. A 10-cm tumor was located at the remnant stomach just proximal to the previous area of anastomosis. Pathologic examination showed well-differentiated SCC extended into the subserosa without lymph node involvement (T3N0M0). The patient received adjuvant systemic chemotherapy with 6 cycles of 5-FU and cisplatin regimen, and he is still alive at the 54-month follow-up. According to the treatment principles of gastric cancer, early detection and radical surgical resection can improve the prognosis.

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          Most cited references 26

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            SQUAMOUS CELL CARCINOMA AND ADENOACANTHOMA OF THE STOMACH. A CLINICOPATHOLOGIC STUDY.

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                Author and article information

                Journal
                J Gastric Cancer
                J Gastric Cancer
                JGC
                Journal of Gastric Cancer
                The Korean Gastric Cancer Association
                2093-582X
                2093-5641
                June 2016
                24 June 2016
                : 16
                : 2
                : 120-124
                Affiliations
                Department of Surgery, Eulji Medical Center, Eulji University College of Medicine, Seoul, Korea.
                [1 ]Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine, Seoul, Korea.
                [2 ]Department of Pathology, Eulji Medical Center, Eulji University College of Medicine, Seoul, Korea.
                Author notes
                Correspondence to: Yeon Soo Chang. Department of Surgery, Eulji Medical Center, Eulji University College of Medicine, 68 Hangeulbiseok-ro, Nowon-gu, Seoul 01830, Korea. Tel: +82-2-970-8688, Fax: +82-2-970-8227, cutdown@ 123456eulji.ac.kr
                Article
                10.5230/jgc.2016.16.2.120
                4944001
                27433399
                Copyright © 2016 by The Korean Gastric Cancer Association

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                Categories
                Case Report

                Oncology & Radiotherapy

                squamous cell carcinoma, stomach neoplasms, gastric stump

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