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      Avaliação de ansiedade e depressão em pacientes oncológicos: comparação psicométrica Translated title: Assessment of anxiety and depression in cancer patients: a psychometric comparison Translated title: Evaluación de la ansiedad y la depresión en pacientes oncológicos: comparación psicométrica

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          Abstract

          Instrumentos de avaliação de ansiedade e depressão são úteis para diagnóstico e orientação do manejo clínico diante das alterações emocionais suscitadas pelas vivências do câncer. O presente estudo comparou vantagens e desvantagens psicométricas de instrumentos comumente utilizados em serviços especializados em Oncologia: Escala de Ansiedade e Depressão (HADS), Transtorno Geral de Ansiedade (GAD-7) e Questionário sobre Saúde do Paciente (PHQ-9). Participaram da pesquisa, 200 pacientes diagnosticados com câncer, em tratamento quimioterápico, sendo 30,5% homens e 69,5% mulheres, com idade entre 18 a 89 anos (M=56,8; DP=15). Os instrumentos mostraram coeficientes de fidedignidade variando entre 0,74 e 0,84. As características psicométricas estudadas indicaram valores melhores para HADS-D e GAD-7. Entretanto, HADS-A e PHQ-9 também se mostraram adequados para avaliação de ansiedade e depressão. Sugere-se a adoção desses instrumentos para triagem, diagnóstico e monitoramento de pacientes com câncer, especialmente nos domínios psicológico e social.

          Translated abstract

          Evaluation tools of anxiety and depression are useful for diagnosis and clinical management orientation before the changes caused by cancer experiences. The present study compared psychometric advantages and disadvantages of instruments commonly used in specialized services in Oncology: Hospital Anxiety and Depression Scale (HADS), General Anxiety Disorder (GAD-7) and the Patient Health Questionnaire (PHQ-9). There were 200 patients diagnosed with cancer and in chemotherapy treatment participating in the study, being 30.5% men and 69.5% women, aged between 18 to 89 years (M=56.8; SD=15). The instruments showed coefficients of reliability varying between .74 and .84. The evaluated psychometric characteristics indicated better values for HADS-D and GAD-7. However, HADS-A and PHQ-9 were also found to be suitable for evaluation of anxiety and depression. We suggest the adoption of these instruments for screening, diagnosis and monitoring of cancer patients, especially in psychological and social domains.

          Translated abstract

          Instrumentos de evaluación de ansiedad y depresión son útiles para el diagnóstico y la orientación del manejo clínico frente a los cambios emocionales originados por las experiencias del cáncer. Este estudio comparó ventajas y desventajas psicométricas de instrumentos utilizados comúnmente en servicios especializados en Oncología: Escala de Ansiedad y Depresión (HADS), Trastorno General de Ansiedad (GAD-7) y Cuestionario sobre la Salud del Paciente (PHQ-9). Participaron del estudio 200 pacientes diagnosticados con cáncer, en tratamiento con quimioterapia, siendo 30,5% hombres y 69,5% mujeres, con edades entre 18 y 89 años (M=56,8; DT=15). Los instrumentos mostraron índices de confiabilidad variando entre 0,74 y 0,84. Las características psicométricas estudiadas mostraron mejores valores para la HADS-D y el GAD-7. Sin embargo, la HADS-A y el PHQ-9 también se mostraron adecuados para la evaluación de la ansiedad y la depresión. Se sugiere adoptar estos instrumentos para la detección, el diagnóstico y el seguimiento de pacientes con cáncer, especialmente en los dominios psicológicos y sociales.

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          Most cited references52

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          A brief measure for assessing generalized anxiety disorder: the GAD-7.

          Generalized anxiety disorder (GAD) is one of the most common mental disorders; however, there is no brief clinical measure for assessing GAD. The objective of this study was to develop a brief self-report scale to identify probable cases of GAD and evaluate its reliability and validity. A criterion-standard study was performed in 15 primary care clinics in the United States from November 2004 through June 2005. Of a total of 2740 adult patients completing a study questionnaire, 965 patients had a telephone interview with a mental health professional within 1 week. For criterion and construct validity, GAD self-report scale diagnoses were compared with independent diagnoses made by mental health professionals; functional status measures; disability days; and health care use. A 7-item anxiety scale (GAD-7) had good reliability, as well as criterion, construct, factorial, and procedural validity. A cut point was identified that optimized sensitivity (89%) and specificity (82%). Increasing scores on the scale were strongly associated with multiple domains of functional impairment (all 6 Medical Outcomes Study Short-Form General Health Survey scales and disability days). Although GAD and depression symptoms frequently co-occurred, factor analysis confirmed them as distinct dimensions. Moreover, GAD and depression symptoms had differing but independent effects on functional impairment and disability. There was good agreement between self-report and interviewer-administered versions of the scale. The GAD-7 is a valid and efficient tool for screening for GAD and assessing its severity in clinical practice and research.
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            The PHQ-9: validity of a brief depression severity measure.

            While considerable attention has focused on improving the detection of depression, assessment of severity is also important in guiding treatment decisions. Therefore, we examined the validity of a brief, new measure of depression severity. The Patient Health Questionnaire (PHQ) is a self-administered version of the PRIME-MD diagnostic instrument for common mental disorders. The PHQ-9 is the depression module, which scores each of the 9 DSM-IV criteria as "0" (not at all) to "3" (nearly every day). The PHQ-9 was completed by 6,000 patients in 8 primary care clinics and 7 obstetrics-gynecology clinics. Construct validity was assessed using the 20-item Short-Form General Health Survey, self-reported sick days and clinic visits, and symptom-related difficulty. Criterion validity was assessed against an independent structured mental health professional (MHP) interview in a sample of 580 patients. As PHQ-9 depression severity increased, there was a substantial decrease in functional status on all 6 SF-20 subscales. Also, symptom-related difficulty, sick days, and health care utilization increased. Using the MHP reinterview as the criterion standard, a PHQ-9 score > or =10 had a sensitivity of 88% and a specificity of 88% for major depression. PHQ-9 scores of 5, 10, 15, and 20 represented mild, moderate, moderately severe, and severe depression, respectively. Results were similar in the primary care and obstetrics-gynecology samples. In addition to making criteria-based diagnoses of depressive disorders, the PHQ-9 is also a reliable and valid measure of depression severity. These characteristics plus its brevity make the PHQ-9 a useful clinical and research tool.
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              The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review.

              Depression, anxiety and somatization are the most common mental disorders in primary care as well as medical specialty populations; each is present in at least 5-10% of patients and frequently comorbid with one another. An efficient means for measuring and monitoring all three conditions would be desirable. Evidence regarding the psychometric and pragmatic characteristics of the Patient Health Questionnaire (PHQ)-9 depression, generalized anxiety disorder (GAD)-7 anxiety and PHQ-15 somatic symptom scales are synthesized from two sources: (1) four multisite cross-sectional studies (three conducted in primary care and one in obstetric-gynecology practices) comprising 9740 patients, and (2) key studies from the literature that have studied these scales. The PHQ-9 and its abbreviated eight-item (PHQ-8) and two-item (PHQ-2) versions have good sensitivity and specificity for detecting depressive disorders. Likewise, the GAD-7 and its abbreviated two-item (GAD-2) version have good operating characteristics for detecting generalized anxiety, panic, social anxiety and post-traumatic stress disorder. The optimal cutpoint is > or = 10 on the parent scales (PHQ-9 and GAD-7) and > or = 3 on the ultra-brief versions (PHQ-2 and GAD-2). The PHQ-15 is equal or superior to other brief measures for assessing somatic symptoms and screening for somatoform disorders. Cutpoints of 5, 10 and 15 represent mild, moderate and severe symptom levels on all three scales. Sensitivity to change is well-established for the PHQ-9 and emerging albeit not yet definitive for the GAD-7 and PHQ-15. The PHQ-9, GAD-7 and PHQ-15 are brief well-validated measures for detecting and monitoring depression, anxiety and somatization. Copyright 2010. Published by Elsevier Inc.
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Journal
                psicousf
                PsicoUSF
                PsicoUSF
                Universidade São Francisco (Itatiba )
                1413-8271
                August 2014
                : 19
                : 2
                : 187-197
                Affiliations
                [1 ] Universidade de Brasília Brazil
                Article
                S1413-82712014000200002
                10.1590/1413-82712014019002004
                f598344d-b231-4897-b2a6-6d94e95bc39e

                http://creativecommons.org/licenses/by/4.0/

                History

                Cancer,Anxiety,Depression,Psychometrics,Statistical measurement,Cáncer,Ansiedad,Depresión,Psicometría,Medidas estadísticas,Câncer,Ansiedade,Depressão,Psicometria,Medidas estatísticas

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