4
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Peripartum cardiomyopathy: a 2022 update Translated title: Miocardiopatía periparto: una actualización de 2022

      review-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Abstract Peripartum cardiomyopathy (PPCM) is a rare but life-threatening condition defined by left ventricular dysfunction and heart failure (HF), occurring in late pregnancy or, more commonly, the early postpartum period. In African American women, women with pre-eclampsia, advanced maternal age, and numerous gestation pregnancies, there is a greater incidence. Although the pathophysiology of PPCM is still undetermined, the importance of vasculo-hormonal pathways has been suggested in research over the past decades. Sarcomere genetic polymorphisms are found in at least some women with the disorder. More than 50% of the patients recover systolic function, albeit some are left with chronic cardiomyopathy, and a small minority of patients requires mechanical support or cardiac transplantation, or both. For the diagnosis of PPCM, electrocardiographic findings of decreased myocardial function are essential. Currently, the management of PPCM is limited to standard treatments for HF with reduced ejection fraction, with attention to minimizing the potential adverse effects on the fetus in women who are still pregnant. As a result, the outcome might range from full recovery to persistent HF, arrhythmia, thromboembolic events, or death. Research on PPCM is examined in this review, as are potential future paths for further study.

          Translated abstract

          Resumen La miocardiopatía periparto (PPCM) es una afección rara pero potencialmente mortal que se define por disfunción ventricular izquierda e insuficiencia cardíaca (IC), que ocurre al final del embarazo o, más comúnmente, al comienzo del período posparto. En mujeres afroamericanas, mujeres con preeclampsia, edad materna avanzada y gestaciones numerosas, existe una mayor incidencia. Aunque la fisiopatología de la PPCM aún no se ha determinado, la importancia de las vías vasculohormonales se ha sugerido en la investigación durante las últimas décadas. Los polimorfismos genéticos del sarcómero se encuentran en algunas mujeres afectas con el trastorno. Más del 50% de los pacientes recuperan la función sistólica, aunque algunos quedan con miocardiopatía crónica y, una pequeña minoría de pacientes, requiere soporte mecánico, trasplante cardíaco, o ambos. Para el diagnóstico de PPCM, los hallazgos electrocardiográficos de función miocárdica disminuida son esenciales. Actualmente, el manejo de la PPCM se limita a los tratamientos estándar para la IC con fracción de eyección reducida, con atención a minimizar los posibles efectos adversos sobre el feto en mujeres que aún están embarazadas. Como resultado, el resultado puede variar desde una recuperación total hasta insuficiencia cardíaca persistente, arritmia, eventos tromboembólicos o muerte. En esta revisión se examina la investigación sobre la PPCM, así como las posibles vías futuras para estudios adicionales.

          Related collections

          Most cited references55

          • Record: found
          • Abstract: not found
          • Article: not found

          2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association.

                Bookmark

                Author and article information

                Journal
                ijm
                Iberoamerican Journal of Medicine
                Iberoam J Med
                Hospital San Pedro (Logroño, La Rioja, Spain )
                2695-5075
                2695-5075
                2022
                : 4
                : 2
                : 104-112
                Affiliations
                [3] Manipal, Karnataka orgnameKasturba Medical College orgdiv1Department of Medicine India
                [2] Bathinda orgnameMax Superspeciality Hospital orgdiv1Department of Cardiology India
                [1] Dubai orgnameAster Hospital orgdiv1Department of Cardiology Emiratos Árabes Unidos
                Article
                S2695-50752022000200005 S2695-5075(22)00400200005
                10.53986/ibjm.2022.0016
                f6557905-00be-42a1-9b2c-482eed6d5ba1

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 30 January 2022
                : 27 March 2022
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 55, Pages: 9
                Product

                SciELO Spain

                Categories
                Review

                Embarazo,Preeclamspia,Insuficiencia cardiaca,Cardiomiopatía,Pregnancy,Pre-eclampsia,Heart failure,Cardiomiopathy

                Comments

                Comment on this article