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      Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract.

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          Abstract

          We investigated the prevalence of single nucleotide polymorphisms in the p16 gene (C540G) and the cyclin D1 gene (G870A), both known to regulate function in G1 arrest and therefore, may play an important role in carcinogenesis.

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          Author and article information

          Journal
          J. Cancer Res. Clin. Oncol.
          Journal of cancer research and clinical oncology
          Springer Nature America, Inc
          0171-5216
          0171-5216
          Dec 2005
          : 131
          : 12
          Affiliations
          [1 ] Institute of Pathology, Heinrich-Heine-University, Postfach 101007, 40001, Duesseldorf, Germany.
          Article
          10.1007/s00432-005-0021-4
          16163549
          f6606c19-b9ba-45d0-b2d2-07bdb837abe5
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