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Possible horizontal transmission of crimean-congo hemorrhagic Fever virus from a mother to her child.

Japanese journal of infectious diseases

therapeutic use, Adult, Antiviral Agents, Child, Preschool, China, Disease Transmission, Infectious, Female, Hemorrhagic Fever Virus, Crimean-Congo, genetics, isolation & purification, Hemorrhagic Fever, Crimean, drug therapy, transmission, virology, Humans, Mothers, RNA, Viral, analysis, blood, Ribavirin

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      The case of a child with Crimean-Congo hemorrhagic fever (CCHF) presumably infected with CCHF virus from her 27-year-old mother is described. The mother with CCHF was treated with ribavirin and did not present with any symptoms of obvious hemorrhage. The child developed fever on the 5th day after the mother's onset. The partial virus genome was amplified by RT-PCR, and nested PCR from the child and the genome sequence were identical to that from the mother, indicating possible transmission of the virus from mother to child. This case indicates the importance of preventive measures for in-house outbreaks of CCHF.

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