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Cyclosporine in severe ulcerative colitis refractory to steroid therapy.
S Lichtiger
1 ,
D H Present ,
A Kornbluth ,
I Gelernt ,
J Bauer ,
G Galler ,
F Michelassi ,
S Hanauer
Jun 30 1994
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Abstract
There has been no new effective drug therapy for patients with severe ulcerative colitis since corticosteroids were introduced almost 40 years ago. In an uncontrolled study, 80 percent of 32 patients with active ulcerative colitis refractory to corticosteroid therapy had a response to cyclosporine therapy.