Record: found
Abstract: found
Article: not found

Assignment of the human cytochrome P-450 nifedipine oxidase gene (CYP3A4) to chromosome 7 at band q22.1 by fluorescence in situ hybridization.

Author(s): T Shimada, K. Horie-Inoue, Kelly Abe, J Inazawa, H. Yamazaki, H Nakagawa, F. Peter Guengerich

Publication date: 1992-05-31

Journal: The Japanese journal of human genetics

Keywords: genetics, Cells, Cultured, Mixed Function Oxygenases, Microscopy, Fluorescence, Lymphocytes, In Situ Hybridization, Humans, Cytochrome P-450 Enzyme System, Cytochrome P-450 CYP3A, Chromosomes, Human, Pair 7, Chromosome Mapping, Chromosome Banding

Read this article at

ScienceOpenPublisher PubMed

Bookmark

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

We have used a full length cDNA clone (2.2 kb) for the human cytochrome P-450 nifedipine oxidase (CYP3A4) enzyme as a probe to determine its chromosome localization by fluorescence in situ hybridization. CYP3A4 was mapped on R-banded human prometaphase chromosomes, and the precise localization of CYP3A4 on chromosome 7 was further confirmed by a delineation of G-banded pattern on the same prometaphase chromosomes through a combination of UV-filter. We assigned CYP3A4 to chromosome 7 at q22.1.

Related collections

Author and article information

Journal

DOI:: 10.1007/BF01899734

PubMed ID:: 1391968

Data availability:

ScienceOpen disciplines: Chemistry

Assignment of the human cytochrome P-450 nifedipine oxidase gene (CYP3A4) to chromosome 7 at band q22.1 by fluorescence in situ hybridization.

Read this article at

Abstract

Related collections

CRISPR/Cas9 editing in human blood

Author and article information

Journal

Comments

Comment on this article

Similar content 519

Cited by 7