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An audit analysis of a guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome.
Sally Johnson
1 ,
Jelena Stojanovic ,
Gema Ariceta ,
Martin Bitzan ,
Nesrin Besbas ,
Michelle Frieling ,
Diana Karpman ,
Daniel Landau ,
Craig Langman ,
Christoph Licht ,
Carmine Pecoraro ,
Magdalena Riedl ,
Ekaterini Siomou ,
Nicole van de Kar ,
Johan Vande Walle ,
Chantal Loirat ,
C Mark Taylor
Oct 2014
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Abstract
In 2009, the European Paediatric Study Group for Haemolytic Uraemic Syndrome (HUS) published a clinical practice guideline for the investigation and initial therapy of diarrhea-negative HUS (now more widely referred to as atypical HUS, aHUS). The therapeutic component of the guideline (comprising early, high-volume plasmapheresis) was derived from anecdotal evidence and expert consensus, and the authors committed to auditing outcome.