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      An audit analysis of a guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome.

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          Abstract

          In 2009, the European Paediatric Study Group for Haemolytic Uraemic Syndrome (HUS) published a clinical practice guideline for the investigation and initial therapy of diarrhea-negative HUS (now more widely referred to as atypical HUS, aHUS). The therapeutic component of the guideline (comprising early, high-volume plasmapheresis) was derived from anecdotal evidence and expert consensus, and the authors committed to auditing outcome.

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          Author and article information

          Journal
          Pediatr. Nephrol.
          Pediatric nephrology (Berlin, Germany)
          1432-198X
          0931-041X
          Oct 2014
          : 29
          : 10
          Affiliations
          [1 ] Great North Children's Hospital, Newcastle Upon Tyne, UK, sally.johnson@nuth.nhs.uk.
          Article
          10.1007/s00467-014-2817-4
          24817340

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