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      Systolic Time-Interval Evaluation by Thermistor Plethysmography during Uninterrupted Dynamic Stress Test in Normals and in Patients with Coronary Artery Disease

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          Abstract

          18 patients with coronary artery disease (CAD) and 21 normal subjects underwent a triangular bicycle exercise test. Systolic time intervals (STI) were calculated at rest and every 2 min during exercise. Under resting conditions, STI were similar in the two groups. During exercise, the ejection time index (ETI), i.e. left ventricular ejection time (LVET) corrected for HR, rose significantly more in CAD patients, as compared to normals. Pre-ejection period (PEP) was also differently affected by exercise in CAD patients, who showed a more shortened PEP (p < 0.001) in the early stage of dynamic stress. PEP/LVET ratio, which in the control group decreased continuously, in CAD patients fell during exercise at lower work loads (p < 0.001), whilst rose during strenuous exercise. Finally, significant differences (p < 0.001) were found in the percent change (%Δ) PEP/LVET ratio between the two groups during the early phase of exercise, in which no superimposition of single values was present. Therefore, this last parameter seems the most reliable to differentiate clearly CAD patients from normal subjects, but its use must be limited at early exercise.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1983
          1983
          07 November 2008
          : 70
          : 6
          : 317-325
          Affiliations
          Institute of Medical Pathology, University of Naples, 2nd School of Medicine, Naples, Italy
          Article
          173614 Cardiology 1983;70:317–325
          10.1159/000173614
          6673826
          © 1983 S. Karger AG, Basel

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          Page count
          Pages: 9
          Categories
          Original Paper

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