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Gaps in African swine fever: Analysis and priorities
September 22 2017
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Abstract
<p class="first" id="d1510407e89">African swine fever (ASF) causes greater sanitary,
social and economic impacts on
swine herds than many other swine diseases. Although ASF was first described in 1921
and it has affected more than fifty countries in Africa, Europe and South America,
several key issues about its pathogenesis, immune evasion and epidemiology remain
uncertain. This article reviews the main characteristics of the causative virus, its
molecular epidemiology, natural hosts, clinical features, epidemiology and control
worldwide. It also identifies and prioritizes gaps in ASF from a horizontal point
of view encompassing fields including molecular biology, epidemiology, prevention,
diagnosis and vaccine development. The purpose of this review is to promote ASF research
and enhance its control.
</p>