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      Changes in employment status prior to initiation of maintenance hemodialysis in the USA from 2006 to 2015

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          Abstract

          Background

          Hemodialysis (HD) patients have high unemployment rates associated with higher mortality and poor quality of life. Changes in employment status prior to dialysis initiation may predict subsequent patient outcomes. We sought to examine US national trends in employment status prior to and at HD initiation, risk factors for job loss and their association with transplantation and mortality.

          Methods

          Employment was defined as working full-time or part-time for 496 989 patients initiating maintenance HD from 2006 to 2015. Associations between patient and dialysis facility characteristics and employment change were analyzed using multivariable logistic regression. Cox regression was used to assess job loss with mortality and transplantation.

          Results

          About 26% ( n = 129 622) of patients were employed 6 months prior compared with 15% ( n = 75 719) at HD initiation. Employment rates 6 months prior to HD initiation decreased from 29% in 2006 to 23% in 2014. Employed patients who maintained employment increased from 57% in 2006 to 64% in 2015. Patients who were older, female, Hispanic, Black, with more comorbidities or living in low-income zip codes were less likely to maintain employment. Facility characteristics associated with employment maintenance included nonprofit status, more stations, dialysis availability after 5 p.m. and home dialysis training. Patients maintaining employment during the 6 months prior to HD had lower mortality and higher transplantation rates than patients who became unemployed.

          Conclusions

          Employment rates among HD patients are low and employment changes common during the 6 months prior to HD. Maintaining employment status was associated with key patient and facility characteristics, kidney transplantation and survival.

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          Most cited references38

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          Effects of unemployment on mental and physical health.

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            Effects of unemployment on mental and physical health.

            From a prospective study of the impact of stress on health in 300 men assessed every six months, men who became unemployed after entering the study were compared with an equal number, matched for age and race, who continued to work. Psychological and health data after unemployment were compared between the two groups by multivariate analysis of variance and covariance. After unemployment, symptoms of somatization, depression, and anxiety were significantly greater in the unemployed than employed. Large standard deviations on self-esteem scores in the unemployed group suggested that some men coped better than others with job-loss stress. Further analysis showed those with higher esteem had more support from family and friends than did those with low self-esteem. Furthermore, unemployed men made significantly more visits to their physicians, took more medications, and spent more days in bed sick than did employed individuals even though the number of diagnoses in the two groups were similar.
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              Comparison of mortality between private for-profit and private not-for-profit hemodialysis centers: a systematic review and meta-analysis.

              Private for-profit and private not-for-profit dialysis facilities provide the majority of hemodialysis care in the United States. There has been extensive debate about whether the profit status of these facilities influences patient mortality. To determine whether a difference in adjusted mortality rates exists between hemodialysis patients receiving care in private for-profit vs private not-for-profit dialysis centers. We searched 11 bibliographic databases, reviewed our own files, and contacted experts in June 2001-January 2002. In June 2002, we also searched PubMed using the "related articles" feature, SciSearch, and the reference lists of all studies that fulfilled our eligibility criteria. We included published and unpublished observational studies that directly compared the mortality rates of hemodialysis patients in private for-profit and private not-for-profit dialysis centers and provided adjusted mortality rates. We masked the study results prior to determining study eligibility, and teams of 2 reviewers independently evaluated the eligibility of all studies. Eight observational studies that included more than 500 000 patient-years of data fulfilled our eligibility criteria. Teams of 2 reviewers independently abstracted data on study characteristics, sampling method, data sources, and factors controlled for in the analyses. Reviewers resolved disagreements by consensus. The studies reported data from January 1, 1973, through December 31, 1997, and included a median of 1342 facilities per study. Six of the 8 studies showed a statistically significant increase in adjusted mortality in for-profit facilities, 1 showed a nonsignificant trend toward increased mortality in for-profit facilities, and 1 showed a nonsignificant trend toward decreased mortality in for-profit facilities. The pooled estimate, using a random-effects model, demonstrated that private for-profit dialysis centers were associated with an increased risk of death (relative risk, 1.08; 95% confidence interval, 1.04-1.13; P<.001). This relative risk suggests that there are annually 2500 (with a plausible range of 1200-4000) excessive premature deaths in US for-profit dialysis centers. Hemodialysis care in private not-for-profit centers is associated with a lower risk of mortality compared with care in private for-profit centers.
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                Author and article information

                Journal
                Clin Kidney J
                Clin Kidney J
                ckj
                Clinical Kidney Journal
                Oxford University Press
                2048-8505
                2048-8513
                June 2020
                14 June 2019
                14 June 2019
                : 13
                : 3
                : 434-441
                Affiliations
                [1 ] Department of Nephrology, Zhongshan Hospital, Fudan University , Shanghai, China
                [2 ] Medical Education Institute , Madison, WI, USA
                [3 ] Department of Psychiatry, Institute for Healthcare Policy & Innovation, University of Michigan , Ann Arbor, MI, USA
                [4 ] Kidney and Dialysis Institute of Shanghai , Shanghai, China
                [5 ] Shanghai Key Laboratory of Kidney and Blood Purification , Shanghai, China
                [6 ] Department of Internal Medicine, Division of Nephrology, University of Michigan , Ann Arbor, MI, USA
                [7 ] Kidney Epidemiology and Cost Center, University of Michigan , Ann Arbor, MI, USA
                Author notes
                Correspondence and offprint requests to: Jennifer L. Bragg-Gresham; E-mail: jennb@ 123456med.umich.edu

                Rajiv Saran and Jennifer L. Bragg-Gresham contributed as joint senior authors.

                Article
                sfz077
                10.1093/ckj/sfz077
                7367129
                32699624
                f83efe38-f5c4-49f3-8786-bf7d77fe3c9b
                © The Author(s) 2019. Published by Oxford University Press on behalf of ERA-EDTA.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

                History
                : 19 February 2019
                : 13 May 2019
                Page count
                Pages: 8
                Funding
                Funded by: NIDDK, DOI 10.13039/100000062;
                Funded by: NIH, DOI 10.13039/100000002;
                Award ID: HHSN276201400001C
                Categories
                Original Articles

                Nephrology
                employment,hemodialysis,mortality,transplantation
                Nephrology
                employment, hemodialysis, mortality, transplantation

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