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      Methoxylated flavones: occurrence, importance, biosynthesis

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      Phytochemistry Reviews

      Springer Science and Business Media LLC

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          Most cited references 176

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          Phytozome: a comparative platform for green plant genomics

          The number of sequenced plant genomes and associated genomic resources is growing rapidly with the advent of both an increased focus on plant genomics from funding agencies, and the application of inexpensive next generation sequencing. To interact with this increasing body of data, we have developed Phytozome (http://www.phytozome.net), a comparative hub for plant genome and gene family data and analysis. Phytozome provides a view of the evolutionary history of every plant gene at the level of sequence, gene structure, gene family and genome organization, while at the same time providing access to the sequences and functional annotations of a growing number (currently 25) of complete plant genomes, including all the land plants and selected algae sequenced at the Joint Genome Institute, as well as selected species sequenced elsewhere. Through a comprehensive plant genome database and web portal, these data and analyses are available to the broader plant science research community, providing powerful comparative genomics tools that help to link model systems with other plants of economic and ecological importance.
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            Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology.

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              Chemistry and Biological Activities of Flavonoids: An Overview

              There has been increasing interest in the research on flavonoids from plant sources because of their versatile health benefits reported in various epidemiological studies. Since flavonoids are directly associated with human dietary ingredients and health, there is need to evaluate structure and function relationship. The bioavailability, metabolism, and biological activity of flavonoids depend upon the configuration, total number of hydroxyl groups, and substitution of functional groups about their nuclear structure. Fruits and vegetables are the main dietary sources of flavonoids for humans, along with tea and wine. Most recent researches have focused on the health aspects of flavonoids for humans. Many flavonoids are shown to have antioxidative activity, free radical scavenging capacity, coronary heart disease prevention, hepatoprotective, anti-inflammatory, and anticancer activities, while some flavonoids exhibit potential antiviral activities. In plant systems, flavonoids help in combating oxidative stress and act as growth regulators. For pharmaceutical purposes cost-effective bulk production of different types of flavonoids has been made possible with the help of microbial biotechnology. This review highlights the structural features of flavonoids, their beneficial roles in human health, and significance in plants as well as their microbial production.
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                Author and article information

                Journal
                Phytochemistry Reviews
                Phytochem Rev
                Springer Science and Business Media LLC
                1568-7767
                1572-980X
                June 2016
                July 28 2015
                June 2016
                : 15
                : 3
                : 363-390
                Article
                10.1007/s11101-015-9426-0
                © 2016

                http://www.springer.com/tdm

                http://www.springer.com/tdm

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