A Review of Deep Learning CT Reconstruction: Concepts, Limitations, and Promise in Clinical Practice

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Purpose of Review

Deep Learning reconstruction (DLR) is the current state-of-the-art method for CT image formation. Comparisons to existing filter back-projection, iterative, and model-based reconstructions are now available in the literature. This review summarizes the prior reconstruction methods, introduces DLR, and then reviews recent findings from DLR from a physics and clinical perspective.

Recent Findings

DLR has been shown to allow for noise magnitude reductions relative to filtered back-projection without suffering from “plastic” or “blotchy” noise texture that was found objectionable with most iterative and model-based solutions. Clinically, early reader studies have reported increases in subjective quality scores and studies have successfully implemented DLR-enabled dose reductions.

Summary

The future of CT image reconstruction is bright; deep learning methods have only started to tackle problems in this space via addressing noise reduction. Artifact mitigation and spectral applications likely be future candidates for DLR applications.

Related collections

Most cited references 84

Record: found
Abstract: found
Article: not found

High-performance medicine: the convergence of human and artificial intelligence

Eric Topol (2019)

The use of artificial intelligence, and the deep-learning subtype in particular, has been enabled by the use of labeled big data, along with markedly enhanced computing power and cloud storage, across all sectors. In medicine, this is beginning to have an impact at three levels: for clinicians, predominantly via rapid, accurate image interpretation; for health systems, by improving workflow and the potential for reducing medical errors; and for patients, by enabling them to process their own data to promote health. The current limitations, including bias, privacy and security, and lack of transparency, along with the future directions of these applications will be discussed in this article. Over time, marked improvements in accuracy, productivity, and workflow will likely be actualized, but whether that will be used to improve the patient-doctor relationship or facilitate its erosion remains to be seen.