A twelve-month survey in three Local Government Areas (LGA) in Nsukka zone, Anambra State, Nigeria revealed that out of 150 local and exotic breeds of pig examined, 46 (30.7%) were infected with trypanosomes. Both single and mixed infections of Trypanosoma brucei and T. congolense were observed. However, T. brucei was the predominant trypanosome encountered. The husbandry system in practice was the most significant factor influencing the prevalence of trypanosomes in the pigs. In addition significantly higher prevalences were recorded during the rainy seasons. Clinical trypanosomosis was encountered in only eight of the 46 positive cases seen, with anaemia, loss of weight and anoestrus being the most important effects associated with these infections. The pathogenic and economic significance of these findings are discussed.