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      Intraocular Pressure in Cushing’s Syndrome

      ,

      Ophthalmic Research

      S. Karger AG

      Cushing’s syndrome, Intraocular pressure, Ophthalmodynamometry, Blood pressure, CVR, CBF, Statistics

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          Abstract

          An ophthalmological examination was done on a group of 70 patients with Cushing’s syndrome. In 47 cases, ophthalmodynamometry was used before and after the operation. The intraocular pressure (IOP), brachial and ophthalmic blood pressure were measured. The cerebrovascular resistance (CVR) and the cerebral blood flow (CBF) were calculated using the method of Niesel and Ismiridis (modification by Weigelin and Lob-stein). After adrenalectomy, a diminution of the IOP, CVR, CBF, brachial and ophthalmic blood pressure occurred. A significant relationship (r = 0.49) was found between the IOP and the mentioned circulatory factors. The measure of determination of only 24% (r<sup>2</sup>) for the interdependence of the multiple correlation shows that other more important factors must be present which are responsible for the diminution of the IOP after the operation. Most probably, a change of facility of aqueous outflow had occurred.

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1975
          1975
          03 December 2009
          : 7
          : 5
          : 390-394
          Affiliations
          Clinical Institute of Experimental Ophthalmology (Direktor: Prof. E. Weigelin), University of Bonn, Bonn
          Article
          264775 Ophthalmic Res 1975;7:390–394
          10.1159/000264775
          © 1975 S. Karger AG, Basel

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          Page count
          Pages: 5
          Categories
          Paper

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