+1 Recommend
1 collections
      • Record: found
      • Abstract: found
      • Article: found

      Intraocular Pressure in Cushing’s Syndrome


      Ophthalmic Research

      S. Karger AG

      Cushing’s syndrome, Intraocular pressure, Ophthalmodynamometry, Blood pressure, CVR, CBF, Statistics

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          An ophthalmological examination was done on a group of 70 patients with Cushing’s syndrome. In 47 cases, ophthalmodynamometry was used before and after the operation. The intraocular pressure (IOP), brachial and ophthalmic blood pressure were measured. The cerebrovascular resistance (CVR) and the cerebral blood flow (CBF) were calculated using the method of Niesel and Ismiridis (modification by Weigelin and Lob-stein). After adrenalectomy, a diminution of the IOP, CVR, CBF, brachial and ophthalmic blood pressure occurred. A significant relationship (r = 0.49) was found between the IOP and the mentioned circulatory factors. The measure of determination of only 24% (r<sup>2</sup>) for the interdependence of the multiple correlation shows that other more important factors must be present which are responsible for the diminution of the IOP after the operation. Most probably, a change of facility of aqueous outflow had occurred.

          Related collections

          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          03 December 2009
          : 7
          : 5
          : 390-394
          Clinical Institute of Experimental Ophthalmology (Direktor: Prof. E. Weigelin), University of Bonn, Bonn
          264775 Ophthalmic Res 1975;7:390–394
          © 1975 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 5


          Comment on this article