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      The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition

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          Abstract

          Early weaned piglets are vulnerable to diarrhea because of weaning stress and immaturity of intestinal tract. Compelling evidence suggests that gut microbiota is vital to host health. However, it is not well understood on the composition and succession of piglet gut microbiota during the weaning transition. In our two trials, total 17 commercial piglets were studied in a pig farm in Jiangxi Province, China. Fresh feces were collected for four times (10 days before weaned, weaned day, 10 days after weaned, 21 days after weaned) by rectal massage. Fecal bacterial composition was assessed by 16S rRNA gene V3–V4 regions sequencing by Illumina Miseq platform. The results showed that the gut microbiota of piglets shifted quickly after weaned and reached relatively stable level in 10 days after weaned. The alpha diversity increased significantly with the age of piglets. The microbiota of suckling piglets was mainly represented by Fusobacterium, Lactobacillus, Bacteroides, Escherichia/Shigella, and Megasphaera. This pattern contrasted with that of Clostridium sensu stricto, Roseburia, Paraprevotella, Clostridium XIVa, and Blautia, which were major representative genera after weaned. In summary, we delineated the development of piglet gut microbiota during the weaning transition. This study helps us understand the maturing development of gut microbiota in commercial piglets.

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          Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

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            Random Forests

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              QIIME allows analysis of high-throughput community sequencing data.

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                Author and article information

                Contributors
                Journal
                Front Microbiol
                Front Microbiol
                Front. Microbiol.
                Frontiers in Microbiology
                Frontiers Media S.A.
                1664-302X
                04 September 2017
                2017
                : 8
                : 1688
                Affiliations
                [1] 1State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University Shanghai, China
                [2] 2Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University Shanghai, China
                Author notes

                Edited by: George Tsiamis, University of Patras, Greece

                Reviewed by: Spyridon Ntougias, Democritus University of Thrace, Greece; Dimitris Tsaltas, Cyprus University of Technology, Cyprus

                *Correspondence: Feng Chen, cf2001@ 123456sjtu.edu.cn

                This article was submitted to Systems Microbiology, a section of the journal Frontiers in Microbiology

                Article
                10.3389/fmicb.2017.01688
                5591375
                28928724
                f963b1a2-681d-44fb-9994-3804a1ca97e9
                Copyright © 2017 Chen, Xu, Chen, Fang, Zhao and Chen.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 18 May 2017
                : 21 August 2017
                Page count
                Figures: 7, Tables: 0, Equations: 0, References: 55, Pages: 13, Words: 0
                Funding
                Funded by: National Natural Science Foundation of China 10.13039/501100001809
                Award ID: 31330005
                Categories
                Microbiology
                Original Research

                Microbiology & Virology
                piglet,development,gut microbiota,weaning,fusobacterium
                Microbiology & Virology
                piglet, development, gut microbiota, weaning, fusobacterium

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