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      Strategies of antioxidant defense.

      1
      European journal of biochemistry
      Wiley

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          Abstract

          Cellular protection against the deleterious effects of reactive oxidants generated in aerobic metabolism, called oxidative stress, is organized at multiple levels. Defense strategies include three levels of protection; prevention, interception, and repair. Regulation of the antioxidant capacity includes the maintenance of adequate levels of antioxidant and the localization of antioxidant compounds and enzymes. Short-term and long-term adaptation and cell specialisation in these functions are new areas of interest. Control over the activity of prooxidant enzymes, such as NADPH oxidase and NO synthases, is crucial. Synthetic antioxidants mimic biological strategies.

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          Author and article information

          Journal
          Eur J Biochem
          European journal of biochemistry
          Wiley
          0014-2956
          0014-2956
          Jul 15 1993
          : 215
          : 2
          Affiliations
          [1 ] Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, Germany.
          Article
          10.1111/j.1432-1033.1993.tb18025.x
          7688300
          f9b8c2cc-a8f0-45f2-85b6-e58438c25744
          History

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