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Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis
Nafees Ahmad ,
Shama D Ahuja ,
Onno W Akkerman ,
Jan-Willem C Alffenaar ,
Laura F Anderson ,
Parvaneh Baghaei ,
Didi Bang ,
Pennan M Barry ,
Mayara L Bastos ,
Digamber Behera ,
Andrea Benedetti ,
Gregory P Bisson ,
Martin J Boeree ,
Maryline Bonnet ,
Sarah K Brode ,
James C M Brust ,
Ying Cai ,
Eric Caumes ,
J Peter Cegielski ,
Rosella Centis ,
Pei-Chun Chan ,
Edward D Chan ,
Kwok-Chiu Chang ,
Macarthur Charles ,
Andra Cirule ,
Margareth Pretti Dalcolmo ,
Lia D'Ambrosio ,
Gerard de Vries ,
Keertan Dheda ,
Aliasgar Esmail ,
Jennifer Flood ,
Gregory J Fox ,
Mathilde Fréchet-Jachym ,
Geisa Fregona ,
Regina Gayoso ,
Medea Gegia ,
Maria Tarcela Gler ,
Sue Gu ,
Lorenzo Guglielmetti ,
Timothy H Holtz ,
Jennifer Hughes ,
Petros Isaakidis ,
Leah Jarlsberg ,
Russell R Kempker ,
Salmaan Keshavjee ,
Faiz Ahmad Khan ,
Maia Kipiani ,
Serena P Koenig ,
Won-Jung Koh ,
Afranio Kritski ,
Liga Kuksa ,
Charlotte L Kvasnovsky ,
Nakwon Kwak ,
Zhiyi Lan ,
Christoph Lange ,
Rafael Laniado-Laborín ,
Myungsun Lee ,
Vaira Leimane ,
Chi-Chiu Leung ,
Eric Chung-Ching Leung ,
Pei Zhi Li ,
Phil Lowenthal ,
Ethel L Maciel ,
Suzanne M Marks ,
Sundari Mase ,
Lawrence Mbuagbaw ,
Giovanni B Migliori ,
Vladimir Milanov ,
Ann C Miller ,
Carole D Mitnick ,
Chawangwa Modongo ,
Erika Mohr ,
Ignacio Monedero ,
Payam Nahid ,
Norbert Ndjeka ,
Max R O'Donnell ,
Nesri Padayatchi ,
Domingo Palmero ,
Jean William Pape ,
Laura J Podewils ,
Ian Reynolds ,
Vija Riekstina ,
Jérôme Robert ,
Maria Rodriguez ,
Barbara Seaworth ,
Kwonjune J Seung ,
Kathryn Schnippel ,
Tae Sun Shim ,
Rupak Singla ,
Sarah E Smith ,
Giovanni Sotgiu ,
Ganzaya Sukhbaatar ,
Payam Tabarsi ,
Simon Tiberi ,
Anete Trajman ,
Lisa Trieu ,
Zarir F Udwadia ,
Tjip S van der Werf ,
Nicolas Veziris ,
Piret Viiklepp ,
Stalz Charles Vilbrun ,
Kathleen Walsh ,
Janice Westenhouse ,
Wing-Wai Yew ,
Jae-Joon Yim ,
Nicola M Zetola ,
Matteo Zignol ,
Dick Menzies
September 2018
September 2018
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Abstract
Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed to estimate
the association of treatment success and death with the use of individual drugs, and
the optimal number and duration of treatment with those drugs in patients with multidrug-resistant
tuberculosis.