Quanxin Long: Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
ValidationRole: Writing – original draftRole: Writing – review & editing
Ran Yan: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ValidationRole: Writing
– original draft
Jieli Hu: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ValidationRole: Writing
– original draft
Dawei Cai: Role: Formal analysisRole: InvestigationRole: ValidationRole: Writing – original draft
Bidisha Mitra:
ORCID: http://orcid.org/0000-0001-6206-2723
Role: InvestigationRole: MethodologyRole: Writing – review & editing
Elena S. Kim: Role: InvestigationRole: Methodology
Alexander Marchetti:
ORCID: http://orcid.org/0000-0001-7845-7375
Role: InvestigationRole: Methodology
Hu Zhang: Role: Investigation
Soujuan Wang:
ORCID: http://orcid.org/0000-0002-3155-209X
Role: InvestigationRole: Methodology
Yuanjie Liu: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Ailong Huang:
ORCID: http://orcid.org/0000-0003-2225-9550
Role: Funding acquisitionRole: Resources
Haitao Guo:
ORCID: http://orcid.org/0000-0002-7146-916X
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: ResourcesRole: SupervisionRole:
Writing – original draftRole: Writing – review & editing
Aleem Siddiqui: Role: Editor
Journal ID (nlm-ta): PLoS Pathog
Journal ID (iso-abbrev): PLoS Pathog
Journal ID (publisher-id): plos
Journal ID (pmc): plospath
Title:
PLoS Pathogens
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7366
ISSN
(Electronic):
1553-7374
Publication date
(Electronic):
29
December
2017
Publication date Collection:
December
2017
Volume: 13
Issue: 12
Electronic Location Identifier: e1006784
Affiliations
[1
]
Department of Microbiology and Immunology, Indiana University School of Medicine,
Indianapolis, Indiana, United States of America
[2
]
Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases,
Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University,
Chongqing, China
University of California, San Diego, UNITED STATES
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PPATHOGENS-D-17-01816
DOI: 10.1371/journal.ppat.1006784
PMC ID: 5747486
PubMed ID: 29287110
SO-VID: fa84197b-6ff6-4ed9-9eca-519f6bcba0cb
Copyright © © 2017 Long et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000060, National Institute of Allergy and Infectious Diseases;
Award ID: R01AI094474
Award Recipient
:
ORCID: http://orcid.org/0000-0002-7146-916X
Haitao Guo
Funded by: funder-id http://dx.doi.org/10.13039/100000060, National Institute of Allergy and Infectious Diseases;
Award ID: R01AI110762
Award Recipient
:
ORCID: http://orcid.org/0000-0002-7146-916X
Haitao Guo
Funded by: funder-id http://dx.doi.org/10.13039/100000060, National Institute of Allergy and Infectious Diseases;
Award ID: R01AI123271
Award Recipient
:
ORCID: http://orcid.org/0000-0002-7146-916X
Haitao Guo
Funded by: Science & Technology Commission of China
Award ID: 2017ZX10202203
Award Recipient
:
ORCID: http://orcid.org/0000-0003-2225-9550
Ailong Huang
This work was supported by the US National Institutes of Health Grant R01AI094474,
R01AI110762 and R01AI123271 (HG), and the Major National S&T program grant 2017ZX10202203
from Science & Technology Commission of China (AH). The funders had no role in study
design, data collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
DNA
Subject:
DNA repair
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
DNA
Subject:
DNA repair
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Enzymology
Subject:
Enzymes
Subject:
Ligases
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Enzymes
Subject:
Ligases
Subject:
Research and Analysis Methods
Subject:
Electrophoretic Techniques
Subject:
Gel Electrophoresis
Subject:
Electrophoretic Blotting
Subject:
Southern Blot
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Molecular Probe Techniques
Subject:
Electrophoretic Blotting
Subject:
Southern Blot
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Molecular Probe Techniques
Subject:
Electrophoretic Blotting
Subject:
Southern Blot
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Artificial Gene Amplification and Extension
Subject:
Polymerase Chain Reaction
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Artificial Gene Amplification and Extension
Subject:
Polymerase Chain Reaction
Subject:
Research and analysis methods
Subject:
Extraction techniques
Subject:
DNA extraction
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
DNA construction
Subject:
Plasmid Construction
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
DNA construction
Subject:
Plasmid Construction
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
DNA
Subject:
DNA replication
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
DNA
Subject:
DNA replication
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
DNA
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Nucleic Acids
Subject:
DNA
