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      Journal of Pain Research (submit here)

      This international, peer-reviewed Open Access journal by Dove Medical Press focuses on reporting of high-quality laboratory and clinical findings in all fields of pain research and the prevention and management of pain. Sign up for email alerts here.

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      Is Open Access

      Greater Pain Severity is Associated with Inability to Access Addiction Treatment Among a Cohort of People Who Use Drugs

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          Abstract

          Aim

          Given that co-occurring pain is prevalent among people who use drugs (PWUD), we sought to explore the effect of pain severity on accessing addiction treatment.

          Methods

          Data were derived from two prospective cohort studies of PWUD in Vancouver, Canada from June 2014 to May 2016. Multivariable generalized linear mixed-effects multiple regression (GLMM) analyses were used to investigate the association between average pain severity and self-reported inability to access addiction treatment.

          Results

          Among 1348 PWUD, 136 (10.1%) reported being unable to access addiction treatment at least once over the study period. Individuals who reported being unable to access addiction treatment had a significantly higher median average pain severity score (median=5, IQR=0–7) compared to individuals reporting no inability to access addiction treatment (median=3, IQR=0–6, p=0.038). Greater pain severity was independently associated with higher odds of reporting inability to access addiction treatment (AOR: 1.75, 95%CI: 1.08–2.82 for mild-moderate vs no pain; AOR: 1.98, 95%CI: 1.27–3.09 for moderate-severe vs no pain).

          Conclusion

          PWUD with greater pain severity may be at higher risk of being unable to access addiction treatment, or vice versa. While further research is needed to confirm causal associations, these data suggest that there may be underlying pathways or mechanisms through which pain may be associated with access to addiction treatment for PWUD.

          Most cited references24

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          The Prescription Opioid and Heroin Crisis: A Public Health Approach to an Epidemic of Addiction

          Annual Review of Public Health, 36(1), 559-574
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            Grading the severity of chronic pain

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              Medication-assisted therapies--tackling the opioid-overdose epidemic.

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                Author and article information

                Journal
                J Pain Res
                J Pain Res
                jpr
                jpainres
                Journal of Pain Research
                Dove
                1178-7090
                01 October 2020
                2020
                : 13
                : 2443-2449
                Affiliations
                [1 ]British Columbia Centre on Substance Use , Vancouver, BC V6Z 2A9, Canada
                [2 ]School of Population and Public Health, University of British Columbia , Vancouver, BC V6T 1Z3, Canada
                [3 ]British Columbia Centre for Excellence in HIV/AIDS, St Paul’s Hospital , Vancouver, BC V6Z 1Y6, Canada
                [4 ]Centre for Urban Health Solutions, St Michael’s Hospital, Li Ka Shing Knowledge Institute , Toronto, ON M5B 1T8, Canada
                [5 ]Faculty of Health Sciences, Simon Fraser University , Burnaby, BC V5A 1S6, Canada
                [6 ]Department of Medicine, University of British Columbia , Vancouver, BC V6Z 2A9, Canada
                Author notes
                Correspondence: Thomas Kerr Department of Medicine, University of British Columbia , 400-1045 Howe Street, Vancouver, BCV6Z 2A9, CanadaTel +1 778 945-7616Fax +1 604 428-5183 Email bccsu-tk@bccsu.ubc.ca
                Author information
                http://orcid.org/0000-0002-4474-2757
                http://orcid.org/0000-0003-3843-2928
                Article
                255438
                10.2147/JPR.S255438
                7534843
                fa965679-ba0d-4ff0-ad53-00eb778d0802
                © 2020 Voon et al.

                This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php).

                History
                : 28 March 2020
                : 11 August 2020
                Page count
                Figures: 1, Tables: 2, References: 28, Pages: 7
                Funding
                Funded by: US National Institutes of Health;
                Award ID: U01DA038886 and U01DA021525
                Funded by: Canadian Institutes of Health Research through the Canadian Research Initiative on Substance Misuse;
                Funded by: CIHR New Investigator Award;
                Award ID: MSH-141971
                Funded by: United States National Institutes of Health;
                Award ID: U01-DA0251525
                This study was supported by the US National Institutes of Health (U01DA038886 and U01DA021525) and the Canadian Institutes of Health Research through the Canadian Research Initiative on Substance Misuse (SMN–139148). This research was undertaken, in part, thanks to funding from the Canada Research Chairs program through a Tier 1 Canada Research Chair in Inner City Medicine which supports Dr Evan Wood. Pauline Voon is supported through a Vanier Canada Graduate Scholarship from the Canadian Institutes of Health Research (CIHR) and a Doctoral Scholarship from The Pierre Elliott Trudeau Foundation. Dr Kanna Hayashi is supported by a CIHR New Investigator Award (MSH-141971), a Michael Smith Foundation for Health Research (MSFHR) Scholar Award, and the St Paul’s Foundation. M-J Milloy is supported by the United States National Institutes of Health (U01-DA0251525), a New Investigator award from the Canadian Institutes of Health Research, and a Scholar Award from the Michael Smith Foundation for Health Research.
                Categories
                Short Report

                Anesthesiology & Pain management
                pain,addiction,substance use,health services,opioid agonist treatment,methadone

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