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      De novo Assembly and Characterization of Patagonian Toothfish Transcriptome and Develop of EST-SSR Markers for Population Genetics

      , , , , , , ,
      Frontiers in Marine Science
      Frontiers Media SA

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          COANCESTRY: a program for simulating, estimating and analysing relatedness and inbreeding coefficients.

          The software package COANCESTRY implements seven relatedness estimators and three inbreeding estimators to estimate relatedness and inbreeding coefficients from multilocus genotype data. Two likelihood estimators that allow for inbred individuals and account for genotyping errors are for the first time included in this user-friendly program for PCs running Windows operating system. A simulation module is built in the program to simulate multilocus genotype data of individuals with a predefined relationship, and to compare the estimators and the simulated relatedness values to facilitate the selection of the best estimator in a particular situation. Bootstrapping and permutations are used to obtain the 95% confidence intervals of each relatedness or inbreeding estimate, and to test the difference in averages between groups. © 2010 Blackwell Publishing Ltd.
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            Microsatellites: genomic distribution, putative functions and mutational mechanisms: a review

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              TiSGeD: a database for tissue-specific genes

              Summary: The tissue-specific genes are a group of genes whose function and expression are preferred in one or several tissues/cell types. Identification of these genes helps better understanding of tissue–gene relationship, etiology and discovery of novel tissue-specific drug targets. In this study, a statistical method is introduced to detect tissue-specific genes from more than 123 125 gene expression profiles over 107 human tissues, 67 mouse tissues and 30 rat tissues. As a result, a novel subject-specialized repository, namely the tissue-specific genes database (TiSGeD), is developed to represent the analyzed results. Auxiliary information of tissue-specific genes was also collected from biomedical literatures. Availability: http://bioinf.xmu.edu.cn/databases/TiSGeD/index.html Contact: appo@bioinf.xmu.edu.cn; zhiliang.ji@gmail.com
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                Author and article information

                Journal
                Frontiers in Marine Science
                Front. Mar. Sci.
                Frontiers Media SA
                2296-7745
                November 29 2019
                November 29 2019
                : 6
                Article
                10.3389/fmars.2019.00720
                fab2ee3f-9b5e-48bb-bdd1-6a902be4ad40
                © 2019

                Free to read

                https://creativecommons.org/licenses/by/4.0/


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