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      • Record: found
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      • Article: found

      Histochemistry and Electron-Microscopic Observation in Two Cases of Granular Dystrophy of the Cornea

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          Abstract

          We report on 2 cases of granular dystrophy (Groenouw type I). We studied the nature and the ultrastructure of the typical stromal deposits by means of histochemical methods and of electron-microscopic examination. These deposits did not stain with Alcian blue, periodic acid-Schiff, Mallory, van Gieson, von Kossa or Congo red so that they are not constituted of proteoglycans, collagen, calcium or amyloid. They probably contain a proteic material. At the electron-microscopic level we observed electron-dense material which was made up of filaments immersed into an amorphous matrix.

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          Author and article information

          Journal
          Journal ID (publisher-id): OPH
          Journal ID (nlm-ta): Ophthalmologica
          Journal ID (doi): 10.1159/issn.0030-3755
          Title: Ophthalmologica
          Publisher: S. Karger AG
          ISSN (Print): 0030-3755
          ISSN (Electronic): 1423-0267
          Publication date Subscription-year: 1991
          Publication date (Print): 1991
          Publication date (Electronic): 31 March 2010
          Volume: 203
          Issue: 4
          Pages: 164-167
          Affiliations
          Chair of Physiopathologic Optics, ‘La Sapienza’ University, Rome, Italy
          Article
          Publisher ID: 310245 Other ID: Ophthalmologica 1991;203:164–167
          DOI: 10.1159/000310245
          PubMed ID: 1723793
          SO-VID: fb2373b2-3f0c-49f3-a2a4-dde81e5704b6
          Copyright © © 1991 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 22 June 1991
          Date accepted : 25 June 1991
          Page count
          Pages: 4
          Categories
          Subject: Original Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Cornea,Histochemistry,Electron microscopy,Dystrophy
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Cornea, Histochemistry, Electron microscopy, Dystrophy

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