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      Beneficial aspects of real time flow measurements for the management of acute right ventricular heart failure following continuous flow ventricular assist device implantation

      case-report

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          Abstract

          Background

          Optimal management of acute right heart failure following the implantation of a left ventricular assist device requires a reliable estimation of left ventricular preload and contractility. This is possible by real-time pump blood flow measurements.

          Clinical case

          We performed implantation of a continuous flow left ventricular assist device in a 66 years old female patient with an end-stage heart failure on the grounds of a dilated cardiomyopathy. Real-time pump blood flow was directly measured by an ultrasonic flow probe placed around the outflow graft.

          Diagnosis

          The progressive decline of real time flow and the loss of pulsatility were associated with an increase of central venous pressure, inotropic therapy and progressive renal failure suggesting the presence of an acute right heart failure. Diagnosis was validated by echocardiography and thermodilution measurements.

          Treatment

          Temporary mechanical circulatory support of the right ventricle was successfully performed. Real time flow measurement proved to be a useful tool for the diagnosis and ultimately for the management of right heart failure including the weaning from extracorporeal membrane oxygenation.

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          Most cited references2

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          Current status of the MicroMed DeBakey Noon Ventricular Assist Device.

          The HeartAttendant programs the controller and sets pump rpm and alarm thresholds. It collects and stores pump parameters when connected to the controller and enables remote monitoring via the Internet. It charges and reconditions the batteries and can provide electrical power from the wall. It eliminates the need for the Clinical Data Acquisition System and the Patient Home Support System. The new controller, in all modes, displays pump flow (L/min), current/amps, power/watts, rpm, and diagnostic and emergency alarms. The HeartAssist 5 is CE-approved in Europe. A new U.S. Food and Drug Administration study of the HeartAssist 5 as a bridge to transplant is being finalized.
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            Application of indirect flow rate measurement using motor driving signals to a centrifugal blood pump with an integrated motor.

            The method of measuring the flow rate of a centrifugal blood pump from the input electric power, which will be indispensable for the long-term use of such devices, was developed and was applied to the direct-driven centrifugal blood pump that has been developed by our research group. The accuracy was evaluated in a chronic animal experiment using an adult goat. The results demonstrated that this method carries the sufficient potential of the instantaneous monitoring method, but errors due to electromagnetic and mechanical losses were not determined always precisely. The detection of adverse phenomena such as the obstruction of the inlet cannula was also possible from the estimated value of the flow rate and its waveform pattern.
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              Author and article information

              Journal
              J Cardiothorac Surg
              J Cardiothorac Surg
              Journal of Cardiothoracic Surgery
              BioMed Central
              1749-8090
              2012
              12 November 2012
              : 7
              : 119
              Affiliations
              [1 ]Department for the Surgical Management of End-stage Heart Failure and Mechanical Circulatory Support, Heart and Vascular Center Duisburg, Fahrner street 133-135, 47169, Duisburg, Germany
              Article
              1749-8090-7-119
              10.1186/1749-8090-7-119
              3514258
              23147084
              fb46ee57-ca8e-411f-83e4-859d4b0a6c15
              Copyright ©2012 Spiliopoulos et al.; licensee BioMed Central Ltd.

              This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

              History
              : 7 September 2012
              : 3 November 2012
              Categories
              Case Report

              Surgery
              ventricular assist devices,heart failure,right ventricle
              Surgery
              ventricular assist devices, heart failure, right ventricle

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