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      Acroisquemia aguda en tiempos de COVID-19. Clínica, evolución y hallazgos de laboratorio Translated title: Acute acro-ischemia in the child at the time of COVID-19. Clinical, evolution and laboratory findings

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          Abstract

          Resumen Un nuevo coronavirus llamado SARS-CoV-2, causante de una pandemia global, afecta a la población pediátrica con unas características clínicas diferentes a las de los adultos. Las lesiones dermatológicas acroisquémicas que se pueden asociar, se manifiestan más en pacientes jóvenes sin cuadro respiratorio. Se presentan tres casos clínicos con estudios analíticos, que incluyen determinación de anticuerpos neutralizantes por inmunocromatografía. En ninguno de los casos se ha podido demostrar la participación del SARS-CoV-2 como agente implicado. El término de "acroisquemia aguda en el niño en tiempos de COVID-19" parece ser el término más adecuado hasta tener un mayor conocimiento del cuadro.

          Translated abstract

          Abstract A new coronavirus called SARSCoV-2, causing a global pandemic, affects the pediatric population with some characteristics different from those of adults. The acro-ischemic dermatological lesions that can be associated, are manifested more in young patients without respiratory symptoms. Three clinical cases with analytical studies that include neutralizing antibody determinations by immunochromatography are presented. In none of these cases the SARS-CoV-2 appears to be an involved agent. The term "acute acro-ischemia in the child in the times of the Covid-19" seems to be the best term until there is a better understanding of the disease.

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          Most cited references22

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          Clinical Characteristics of Coronavirus Disease 2019 in China

          Abstract Background Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. Methods We extracted data regarding 1099 patients with laboratory-confirmed Covid-19 from 552 hospitals in 30 provinces, autonomous regions, and municipalities in mainland China through January 29, 2020. The primary composite end point was admission to an intensive care unit (ICU), the use of mechanical ventilation, or death. Results The median age of the patients was 47 years; 41.9% of the patients were female. The primary composite end point occurred in 67 patients (6.1%), including 5.0% who were admitted to the ICU, 2.3% who underwent invasive mechanical ventilation, and 1.4% who died. Only 1.9% of the patients had a history of direct contact with wildlife. Among nonresidents of Wuhan, 72.3% had contact with residents of Wuhan, including 31.3% who had visited the city. The most common symptoms were fever (43.8% on admission and 88.7% during hospitalization) and cough (67.8%). Diarrhea was uncommon (3.8%). The median incubation period was 4 days (interquartile range, 2 to 7). On admission, ground-glass opacity was the most common radiologic finding on chest computed tomography (CT) (56.4%). No radiographic or CT abnormality was found in 157 of 877 patients (17.9%) with nonsevere disease and in 5 of 173 patients (2.9%) with severe disease. Lymphocytopenia was present in 83.2% of the patients on admission. Conclusions During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness. Patients often presented without fever, and many did not have abnormal radiologic findings. (Funded by the National Health Commission of China and others.)
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            Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

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              Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

              In December 2019, a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) emerged in China and has spread globally, creating a pandemic. Information about the clinical characteristics of infected patients who require intensive care is limited.
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                Author and article information

                Journal
                pap
                Pediatría Atención Primaria
                Rev Pediatr Aten Primaria
                Asociación Española de Pediatría de Atención Primaria (Madrid, Madrid, Spain )
                1139-7632
                September 2020
                : 22
                : 87
                : 295-303
                Affiliations
                [2] Asturias orgnameInstituto de Investigación Sanitaria del Principado de Asturias (ISPA) España
                [1] Oviedo Asturias orgnameCentro de Salud La Corredoria España
                Article
                S1139-76322020000400014 S1139-7632(20)02208700014
                fb53d78b-909d-499b-9839-664fe637f5ad

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 22, Pages: 9
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                SciELO Spain

                Categories
                Notas Clínicas

                SARS-CoV-2,Niños,Exantema,Enfermedad viral cutánea,Enfermedad vascular cutánea,COVID-19,Vascular skin disease,Skin diseases, viral,Exanthema,Children

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