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      Parent Report of Health Related Quality of Life in Young Children in Rural Guatemala: Implementation, Reliability, and Validity of the PedsQL in Stunting and Wasting

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          Abstract

          In this study, we review the implementation, reliability, and validity of the Pediatric Quality of Life Inventory (PedsQL), a measure of health-related quality of life, in young children in rural Guatemala. Mothers of 842 children ( age range = 1-60 months) completed the PedsQL Generic Core Scales 4.0 serially for 1 year. Low (Pearson’s r = 0.28, P < .0001) to moderate (Pearson’s r = 0.65, P < .0001) consistency in responding over time was shown. The PedsQL did not discriminate reliably between healthy children and those with stunting or wasting. PedsQL scores were not lower during the time of an acute illness. While we found low to moderate evidence for the reliability of the PedsQL in healthy children, it did not discriminate between healthy children and those with stunting, wasting or other acute illness.

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          Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measures

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            Maternal and child undernutrition: global and regional exposures and health consequences.

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              Cross-cultural adaptation of health-related quality of life measures: Literature review and proposed guidelines

              Clinicians and researchers without a suitable health-related quality of life (HRQOL) measure in their own language have two choices: (1) to develop a new measure, or (2) to modify a measure previously validated in another language, known as a cross-cultural adaptation process. We propose a set of standardized guidelines for this process based on previous research in psychology and sociology and on published methodological frameworks. These guidelines include recommendations for obtaining semantic, idiomatic, experiential and conceptual equivalence in translation by using back-translation techniques and committee review, pre-testing techniques and re-examining the weight of scores. We applied these guidelines to 17 cross-cultural adaptation of HRQOL measures identified through a comprehensive literature review. The reporting standards varied across studies but agreement between raters in their ratings of the studies was substantial to almost perfect (weighted kappa = 0.66-0.93) suggesting that the guidelines are easy to apply. Further research is necessary in order to delineate essential versus optional steps in the adaptation process.
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                Author and article information

                Journal
                Glob Pediatr Health
                Glob Pediatr Health
                GPH
                spgph
                Global Pediatric Health
                SAGE Publications (Sage CA: Los Angeles, CA )
                2333-794X
                27 January 2021
                2021
                : 8
                : 2333794X21991028
                Affiliations
                [1 ]Children’s Hospital Colorado, Aurora, CO, USA
                [2 ]University of Colorado School of Medicine, Aurora, CO, USA
                [3 ]Colorado School of Public Health, Aurora, CO, USA
                [4 ]Fundación para la Salud Integral de los Guatemaltecos, Retalhuleu, Guatemala
                [5 ]Department of Molecular Virology and Microbiology, Baylor College of Medicine
                [6 ]Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
                Author notes
                [*]Amy K. Connery, Children’s Hospital Colorado, 13123 East 16th Ave., 285, Aurora, CO 80045-7106, USA. Email: Amy.connery@ 123456childrenscolorado.org
                [*]

                Co-senior authors.

                Author information
                https://orcid.org/0000-0002-8595-8167
                Article
                10.1177_2333794X21991028
                10.1177/2333794X21991028
                7868501
                fb73cff4-d270-4920-8438-ce4be6a68b58
                © The Author(s) 2021

                This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License ( https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ( https://us.sagepub.com/en-us/nam/open-access-at-sage).

                History
                : 25 November 2020
                : 19 January 2021
                : 7 January 2021
                Funding
                Funded by: The National Institutes of Allergy and Infectious Diseases at the National Institutes of Health, ;
                Award ID: HHSN27200013-16-0057.C1D1.0058
                Categories
                Original Research Article
                Custom metadata
                January-December 2021
                ts1

                pedsql,stunting,wasting,low resource settings,guatemala
                pedsql, stunting, wasting, low resource settings, guatemala

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