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      Supervivencia de los pacientes con cáncer en Navarra y comparación con España Translated title: Survival of cancer patients in Navarre and comparison with Spain

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          RESUMEN

          Fundamento:

          Analizar la supervivencia de pacientes adultos diagnosticados de cáncer en Navarra, describir su tendencia y compararla con la supervivencia en España.

          Métodos:

          Los casos de personas adultas diagnosticadas de cáncer en los periodos 1999-2007 y 2008-2016 fueron seleccionados del registro poblacional de cáncer de Navarra; su estado vital se había actualizado hasta 2020. La supervivencia observada, la supervivencia neta (SN) y la SN estandarizada por edad (SNe) a cinco años, junto con sus intervalos de confianza al 95%, fueron estimados globalmente y para veintinueve grupos de cáncer.

          Resultados:

          Se analizaron 57.564 casos. La SNe de los hombres y mujeres diagnosticados en 2008-2016 fue 59,9% (59,1-60,8) y 63,8% (62,8-64,7), respectivamente. En hombres varió desde 13,4% (10,4-17,4) en cáncer de páncreas hasta 94,0% (88,1-100) en el de tiroides, y en mujeres desde 11,9% (7,2-19,7) en el cáncer de hígado hasta 95,6% (92,6-98,6) en el de tiroides. En comparación con los casos diagnosticados en 1999-2007, la SNe aumentó en diez grupos de cáncer, resultando un incremento global de 5,1 (4,1-6,0) puntos porcentuales. La SNe en Navarra fue 2,7 (1,9-3,4) puntos porcentuales mayor que la descrita en España en 2008-2013.

          Conclusiones:

          En Navarra la supervivencia de pacientes diagnosticados de cáncer en el periodo 2008-2016 mejoró significativamente respecto al periodo 1999-2007. Esta mejora obedece probablemente a múltiples factores, incluyendo diagnósticos más tempranos, opciones terapéuticas más efectivas y mejora del proceso asistencial. La supervivencia global fue mayor en las mujeres que en los hombres. Además, los resultados sugieren una supervivencia más alta en Navarra en comparación con España.

          ABSTRACT

          Background:

          To analyze the survival of adult cancer patients in Navarre, describe its trend, and compare the data for this Spanish Autonomous Community against that reported for Spain.

          Methods:

          Records of adult cancer patients were retrieved from the Navarre’s population-based cancer registry for two periods (1999-2007 and 2008-2016). The vital status had been updated to 2020. Observed survival, net survival and age-standardized net survival at five years with 95% confidence intervals were estimated overall and for twenty-nine cancer groups

          Results:

          We analyzed 57,564 cases. Age-standardized net survival was 59.9% (59.1-60.8) and 63.8% (62.8-64.7) for males and females diagnosed with cancer during the 2008-2016 period, respectively. Age-standardized net survival ranged from 13.4% (10.4-17.4) for pancreatic cancer to 94.0% (88.1-100) for thyroid cancer in male patients, and from 11.9% (7.2-19.7) for liver cancer to 95.6% (92.6-98.6-%) for thyroid cancer in female patients. Compared with cases diagnosed in the 1999-2007 period, age-standardized net survival increased in 10 cancer groups, resulting in an overall increase of 5.1 (4.1-6.0) percentage points. The age-standardized net survival in Navarre was 2.7 (1.9-3.4) percentage points higher than that described for Spain for the 2008-2013 period.

          Conclusions:

          In Navarre, the survival of cancer patients diagnosed during the 2008-2016 period improved significantly in comparison to the 1999-2007 period. Different factors may explain this improvement, including earlier diagnoses, more effective treatment options, and better healthcare processes. Overall, survival was higher in women than in men. Our results suggest a higher survival rate in Navarre than in Spain.

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          Most cited references43

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          Cancer statistics, 2022

          Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population-based cancer occurrence and outcomes. Incidence data (through 2018) were collected by the Surveillance, Epidemiology, and End Results program; the National Program of Cancer Registries; and the North American Association of Central Cancer Registries. Mortality data (through 2019) were collected by the National Center for Health Statistics. In 2022, 1,918,030 new cancer cases and 609,360 cancer deaths are projected to occur in the United States, including approximately 350 deaths per day from lung cancer, the leading cause of cancer death. Incidence during 2014 through 2018 continued a slow increase for female breast cancer (by 0.5% annually) and remained stable for prostate cancer, despite a 4% to 6% annual increase for advanced disease since 2011. Consequently, the proportion of prostate cancer diagnosed at a distant stage increased from 3.9% to 8.2% over the past decade. In contrast, lung cancer incidence continued to decline steeply for advanced disease while rates for localized-stage increased suddenly by 4.5% annually, contributing to gains both in the proportion of localized-stage diagnoses (from 17% in 2004 to 28% in 2018) and 3-year relative survival (from 21% to 31%). Mortality patterns reflect incidence trends, with declines accelerating for lung cancer, slowing for breast cancer, and stabilizing for prostate cancer. In summary, progress has stagnated for breast and prostate cancers but strengthened for lung cancer, coinciding with changes in medical practice related to cancer screening and/or treatment. More targeted cancer control interventions and investment in improved early detection and treatment would facilitate reductions in cancer mortality.
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            Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

            In 2015, the second cycle of the CONCORD programme established global surveillance of cancer survival as a metric of the effectiveness of health systems and to inform global policy on cancer control. CONCORD-3 updates the worldwide surveillance of cancer survival to 2014.
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              • Article: not found

              Progress in cancer survival, mortality, and incidence in seven high-income countries 1995–2014 (ICBP SURVMARK-2): a population-based study

              Population-based cancer survival estimates provide valuable insights into the effectiveness of cancer services and can reflect the prospects of cure. As part of the second phase of the International Cancer Benchmarking Partnership (ICBP), the Cancer Survival in High-Income Countries (SURVMARK-2) project aims to provide a comprehensive overview of cancer survival across seven high-income countries and a comparative assessment of corresponding incidence and mortality trends.
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                Author and article information

                Contributors
                Role: ConceptualizaciónRole: MetodologíaRole: Análisis formalRole: Redacción y preparación del borradorRole: Revisión y edición
                Role: Recogida de la información, codificación y verificaciónRole: Revisión y edición
                Role: Recogida de la información, codificación y verificaciónRole: Revisión y edición
                Role: Recogida de la información, codificación y verificaciónRole: Revisión y edición
                Role: Recogida de la información, codificación y verificaciónRole: Revisión y edición
                Role: Recogida de la información, codificación y verificaciónRole: Revisión y edición
                Role: MetodologíaRole: Revisión y edición
                Role: ConceptualizaciónRole: Recogida de la información, codificación y verificaciónRole: MetodologíaRole: Redacción y preparación del borradorRole: Revisión y edición
                Journal
                An Sist Sanit Navar
                An Sist Sanit Navar
                assn
                Anales del Sistema Sanitario de Navarra
                Gobierno de Navarra. Departamento de Salud
                1137-6627
                2340-3527
                May-Aug 2023
                16 August 2023
                : 46
                : 2
                : e1042
                Affiliations
                [1 ] orgdiv2Instituto de Salud Pública y Laboral de Navarra orgdiv1Departamento de Salud orgnameGobierno de Navarra Pamplona, España
                [2 ] orgnameCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública Madrid, España
                [3 ] orgnameInstituto de Investigación Sanitaria de Navarra Pamplona, España
                Author notes
                [Correspondencia ] Marcela Guevara [ mguevare@ 123456navarra.es ]

                Conflictos de intereses: Los autores declaran no tener conflictos de intereses.

                Author information
                http://orcid.org/0000-0001-9242-6364
                http://orcid.org/0000-0001-6537-0131
                http://orcid.org/0000-0001-8434-2013
                Article
                10.23938/ASSN.1042
                10498136
                37594062
                fb82cedd-fb42-4575-b2ca-c6a78780deb0

                Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons (CC BY-SA 4.0)

                History
                : 01 March 2023
                : 25 April 2023
                : 01 June 2023
                Page count
                Figures: 4, Tables: 4, Equations: 0, References: 37, Pages: 0
                Categories
                Artículos Originales

                cáncer,supervivencia,pronóstico,tendencias,registro de cáncer,cancer,survival,prognosis,trends,cancer registry

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