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      Alkaline encrusted pyelitis.

      1 , , , ,
      Acta clinica Belgica
      Maney Publishing

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          Abstract

          Alkaline encrusted pyelitis is an infectious disease characterised by encrustations in the wall of the upper urinary tract, surrounded by severe inflammation. Destruction of native kidneys and kidney grafts may occur, resulting in end stage renal failure. Corynebacterium group D2, an urea splitting microorganism, is nearly exclusively associated with this disease. The most important predisposing factors are previous urological procedures and an immunosuppressed state. In a suggestive clinical context, diagnosis should be made with unenhanced computed tomography findings and bacteriologic isolation of the responsible microorganism. The treatment is threefold: appropriate antibiotic therapy, by preference with glycopeptides, acidification of urine and chemolysis, and if needed, surgical removal of encrustations. We report the case of a patient who was diagnosed with this rare condition and could escape maintenance dialysis after correct diagnosis was made and conservative treatment was started using antibiotics and combined oral and local acidification.

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          Author and article information

          Journal
          Acta Clin Belg
          Acta clinica Belgica
          Maney Publishing
          1784-3286
          1784-3286
          March 1 2006
          : 60
          : 6
          Affiliations
          [1 ] Department of Nephrology, University Hospital Gasthuisberg, 3000 Leuven, Belgium. saimen@fil-saimen.be
          Article
          10.1179/acb.2005.055
          16502598
          fbd35b99-12ba-40df-b4fa-234fc88802e6
          History

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