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      A Mechanism-Based Approach to Physical Therapist Management of Pain

      1 , 2 , 3

      Physical Therapy

      Oxford University Press (OUP)

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          Most cited references 102

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          Case-finding instruments for depression

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            Systematic literature review of imaging features of spinal degeneration in asymptomatic populations.

            Degenerative changes are commonly found in spine imaging but often occur in pain-free individuals as well as those with back pain. We sought to estimate the prevalence, by age, of common degenerative spine conditions by performing a systematic review studying the prevalence of spine degeneration on imaging in asymptomatic individuals.
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              Can we conquer pain?

              Pain can be an adaptive sensation, an early warning to protect the body from tissue injury. By the introduction of hypersensitivity to normally innocuous stimuli, pain may also aid in repair after tissue damage. Pain can also be maladaptive, reflecting pathological function of the nervous system. Multiple molecular and cellular mechanisms operate alone and in combination within the peripheral and central nervous systems to produce the different forms of pain. Elucidation of these mechanisms is key to the development of treatments that specifically target underlying causes rather than just symptoms. This new approach promises to revolutionize pain diagnosis and management.
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                Author and article information

                Journal
                Physical Therapy
                Oxford University Press (OUP)
                0031-9023
                1538-6724
                May 2018
                May 2018
                May 01 2018
                April 16 2018
                : 98
                : 5
                : 302-314
                Affiliations
                [1 ]Department of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa
                [2 ]Department of Physical Therapy and Rehabilitation Science, University of Iowa
                [3 ]Department of Physical Therapy and Rehabilitation Science, 1-242 MEB, University of Iowa, Iowa City, IA 52242 (USA)
                Article
                10.1093/ptj/pzy030
                © 2018

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