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      Idiopathic Membranous Glomerulonephritis Associated with Diabetes mellitus

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          Abstract

          The present study described 3 patients with idiopathic membranous glomerulonephritis associated with diabetes mellitus. Clinical characteristics of the 3 patients contrasted with diabetic glomerulosclerosis in the following manner: absence of diabetic retinopathy and neuropathy, and presence of nephrotic syndrome associated with relatively short duration of diabetes mellitus. Renal histology showed the characteristic changes of membranous glomerulonephritis along with those of diabetic glomerulosclerosis. Immunofluorescent studies demonstrated a granular pattern of IgG and C<sub>3</sub> deposits along the glomerular capillary wall. Electron microscopic study also demonstrated thickening of glomerular basement membrane and increase of mesangial matrix as well as the presence of electron-dense deposits primarily in the subepithelial and mesangial areas.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1981
          1981
          02 December 2008
          : 28
          : 4
          : 163-168
          Affiliations
          Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
          Article
          182163 Nephron 1981;28:163–168
          10.1159/000182163
          7301001
          © 1981 S. Karger AG, Basel

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          Page count
          Pages: 6
          Categories
          Original Paper

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