L. Hoin , M. Palun , A. Gallo , V. Sladeckova , B. Durcova , J. Bencova , L. Matulnikova , M. Sramkova , P. Cmorej , P. Vansac , P.H. Ali , E. Grey
October 27 2018
October 27 2018
Background: Orphan status is usually a risk factor for many diseases and results in social exclusion and worse outcomes than children with parents. Methods: The case reports of severe toxicity where death was averted by close monitoring in an orphanage in Phnom Penh, Cambodia are presented. Results: Close monitoring of adherence of antiretroviral therapy (ARV) is possible only in close facility, e.g. orphanage, where regular DOT (directly observed therapy) and DOTOX (directly observed toxicity) is possible. Conclusions: Three cases of severe toxicity: two bone marrow severe suppression and one cardiomyopathy are presented. Deaths were averted by close observation and early interventions.
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