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      Síndrome Anémico: Carcinoide Gástrico tipo 1 (Papel de la Ultrasonografía endoscópica en el diagnóstico y tratamiento) Translated title: Anemia Syndrome: Type 1 Gastric Carcinoid (Role of endoscopic ultrasound in the diagnosis and treatment)

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          Abstract

          Se presenta el caso de un varón de 74 años que ingresa en Medicina Interna por un cuadro de Anemia grave sintomática, alcanzando el diagnóstico de Tumor Neuroendocrino subtipo Carcinoide Gástrico tipo 1 de la Clasificación de Rindi y cols. El papel de la ultrasonografía endoscópica fue crucial para un correcto diagnóstico y tratamiento del paciente. Posteriormente se expone una revisión del estado actual de recomendaciones para un correcto diagnóstico y tratamiento de este tipo de tumores.

          Translated abstract

          We report a case of a 74 year old man who was admitted to our Internal Medicine Department for severe symptomatic anemia. He was diagnosed with a type 1 gastric neuroendocrine tumor classified according to Rindi et al, Endoscopic ultrasound was the key for correct diagnosis and patient management. Subsequently, we present a review of the current status of the recommendations for the correct diagnosis and treatment in this type of tumor.

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          Most cited references15

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          Endoscopic mucosal resection in the management of gastric carcinoid tumors.

          Gastric carcinoid tumors are a rare disease. Previously, total gastrectomy was regarded as the treatment of choice. However, differences in biological malignancy have recently led to the increased use of endoscopic mucosal resection (EMR) for treatment. We studied the outcome of EMR in patients with gastric carcinoids who were treated at our hospital and discuss the indications for endoscopic treatment. Between 1986 and 1999 we carried out gastric mucosal resection in five patients with gastric carcinoid tumors. The procedure used for EMR was either strip biopsy or endoscopic aspiration mucosectomy. The carcinoid tumors measured 10 mm or less in four of the five patients. Two patients had type A gastritis, and all had hypergastrinemia. There was no evidence of recurrence during follow-up (range 6 - 66 months; mean 32.6 months). EMR is useful in the management of type 1 gastric carcinoids as classified by Rindi (hypergastrinemia; tumor diameter of 10 mm or less).
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            Pathology and nomenclature of human gastrointestinal neuroendocrine (carcinoid) tumors and related lesions.

            The pathology and nomenclature of the neuroendocrine cell proliferations in the gut are reviewed. The neoplastic lesions are discussed within the light of a new classification system that attempts to consider the morphologic, functional, and biologic features of the tumors.
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              Gastroscopic screening for gastric carcinoids and carcinoma in pernicious anemia.

              Among 196 patients examined in 1972-1985 because of pernicious anemia (PA), 105 patients under the age of 76 years were invited for gastroscopic screening, and 71 patients (68%) participated. Gastroscopy revealed carcinoid tumor(s) in 5 patients (7%) but no case of carcinoma. In addition, one patient with gastric carcinoid, 5 patients with adenocarcinomas and one with a concomitant carcinoid and carcinoma had already been diagnosed earlier in the overall PA group on the basis of clinical symptoms. Thus, within a follow-up of 0-20 years (mean 7 years) the total frequency of gastric carcinoid tumors was 4% and that of carcinoma 3%. Patients with carcinoid tumors had a long duration of PA and young age of onset; these cases were not necessarily those with the highest serum gastrin levels. Even though most gastric carcinoids are small subclinical tumors of uncertain clinical significance, their unexpectedly high frequency, combined within the risk of carcinoma in PA, might indicate the need for gastroscopic follow-up, at least in cases of juvenile onset PA.
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                albacete
                Revista Clínica de Medicina de Familia
                Rev Clin Med Fam
                Sociedad Castellano-Manchega de Medicina de Familia y Comunitaria (Cuenca, Castilla La Mancha, Spain )
                1699-695X
                October 2010
                : 3
                : 3
                : 217-219
                Affiliations
                [02] Albacete orgnameComplejo Hospitalario Universitario de Albacete orgdiv1Servicio de Medicina Interna España
                [01] Albacete orgnameComplejo Hospitalario Universitario de Albacete orgdiv1Servicio de Cardiología España
                [03] Albacete orgnameComplejo Hospitalario Universitario de Albacete orgdiv1Servicio de Aparato Digestivo España
                Article
                S1699-695X2010000300010
                10.4321/s1699-695x2010000300010
                fc4e3dbc-0e8a-487c-bcd3-695e5e9bf6d2

                This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 International License.

                History
                : 30 July 2010
                : 07 May 2010
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 9, Pages: 3
                Product

                SciELO Spain


                Anemia Perniciosa,Ultrasonografía Endoscópica,Tumor Carcinoide,Anemia,Pernicious,Endosonography,Carcinoid Tumor

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