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      A case of Fournier's gangrene caused by Rothia dentocariosa

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          Abstract

          Abstract We report a case of Fournier's gangrene rescued by debridement. A 40-year-old male patient had a 2x2 cm draining ulcer and 1x2 cm necrotic area in the scrotum for about a month. The patient was diagnosed with Fournier's gangrene. Septic shock and disseminated intravascular coagulation were absent. Computed tomography scan showed soft tissue gas in the scrotum but no gas in the retroperitoneal space or abdominal wall. Debridement was performed. Gangrene of the scrotum and necrosis of the testicle was also seen. Rothia dentocariosa was isolated in extracted wound cultures. He was saved after debridement and administration of strong antibiotics. This is the first case of Fournier's gangrene caused by R. dentocariosa in the available literature.

          Translated abstract

          Resumen Presentamos un caso de gangrena de Fournier rescatado mediante desbridamiento. Un paciente varón de 40 años presentó una úlcera supurante de 2x2 cm y un área necrótica de 1x2 cm en el escroto durante aproximadamente un mes. El paciente fue diagnosticado con gangrena de Fournier. El shock séptico y la coagulación intravascular diseminada estaban ausentes. La tomografía computarizada mostró gas en los tejidos blandos del escroto, pero no en el espacio retroperitoneal ni en la pared abdominal. Se realizó desbridamiento. También se observó gangrena del escroto y necrosis del testículo. Se aisló Rothia dentocariosa en cultivos extraídos de heridas. Se salvó después del desbridamiento y la administración de antibióticos fuertes. Este es el primer caso de gangrena de Fournier por R. dentocariosa en la literatura disponible.

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          Association of sputum microbiota profiles with severity of community-acquired pneumonia in children

          Background Competitive interactions among bacteria in the respiratory tract microbiota influence which species can colonize and potentially contribute to pathogenesis of community-acquired pneumonia (CAP). However, understanding of the role of respiratory tract microbiota in the clinical course of pediatric CAP is limited. Methods We sought to compare microbiota profiles in induced sputum and nasopharyngeal/oropharyngeal (NP/OP) samples from children and to identify microbiota profiles associated with CAP severity. We used 16S ribosomal RNA sequencing and several measures of microbiota profiles, including principal component analysis (PCA), to describe the respiratory microbiota in 383 children, 6 months to <18 years, hospitalized with CAP. We examined associations between induced sputum and NP/OP microbiota profiles and CAP severity (hospital length of stay and intensive care unit admission) using logistic regression. Results Relative abundance of bacterial taxa differed in induced sputum and NP/OP samples. In children 6 months to < 5 years, the sputum PCA factor with high relative abundance of Actinomyces, Veillonella, Rothia, and Lactobacillales was associated with decreased odds of length of stay ≥ 4 days [adjusted odds ratio (aOR) 0.69; 95 % confidence interval (CI) 0.48–0.99]. The sputum factor with high relative abundance of Haemophilus and Pasteurellaceae was associated with increased odds of intensive care unit admission [aOR 1.52; 95 % CI 1.02–2.26]. In children 5 to < 18 years, the sputum factor with high relative abundance of Porphyromonadaceae, Bacteriodales, Lactobacillales, and Prevotella was associated with increased odds of length of stay ≥ 4 days [aOR 1.52; 95 % CI 1.02–2.26]. Taxa in NP/OP samples were not associated with CAP severity. Conclusion Certain taxa in the respiratory microbiota, which were detected in induced sputum samples, are associated with the clinical course of CAP. Electronic supplementary material The online version of this article (doi:10.1186/s12879-016-1670-4) contains supplementary material, which is available to authorized users.
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            Rothia dentocariosa Endocarditis: An Especially Rare Case in a Previously Healthy Man.

            Rothia dentocariosa is a rare gram-positive bacterial organism, one of the group of microbes that normally resides in the mouth and respiratory tract. R. dentocariosa rarely causes disease. Documented cases occur chiefly in patients with valvular or dental disease, or both. We report the case of a previously healthy 58-year-old man who presented with evidence of bacterial endocarditis caused by this organism-which originated from an elusive source. His endocarditis was successfully treated with mitral valve replacement and the administration of antibiotic agents.
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              Rothia dentocariosa, endocarditis and mycotic aneurysms: case report and review of the literature.

              Rothia dentocariosa is a rare cause of endocarditis. It occurs most frequently in patients with prior heart conditions. Although the clinical course is typically subacute, it has a high rate of complications. In particular, the reported incidence of mycotic aneurysms is as high as 25%. Penicillin is the treatment of choice, but additional complications may necessitate prompt surgical intervention. As far as we know, this paper reports the first case of repeated subarachnoid hemorrhages due to R. dentocariosa endocarditis.
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                Author and article information

                Journal
                ijm
                Iberoamerican Journal of Medicine
                Iberoam J Med
                Hospital San Pedro (Logroño, La Rioja, Spain )
                2695-5075
                2695-5075
                2023
                : 5
                : 2
                : 84-87
                Affiliations
                [2] Çanakkale orgnameÇanakkale Onsekiz Mart University, Faculty of Medicine orgdiv1Department of Infectious Diseases and Clinical Microbiology Turquía
                [3] Samsun orgnameVezirköprü State Hospital orgdiv1Department of Urology Turquía
                [1] Osmaniye orgnameKadirli State Hospital orgdiv1Department of İnfectious Diseases and Clinical Microbiology Turquía
                Article
                S2695-50752023000200005 S2695-5075(23)00500200005
                10.53986/ibjm.2023.0012
                fc60ed9a-7a93-484f-aa81-98487b60a384

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 28 January 2023
                : 18 March 2023
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 17, Pages: 4
                Product

                SciELO Spain

                Categories
                Case Report

                Rothia dentocariosa,Rothia,Gangrena de Fournier,Fournier's gangrene

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