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The Relationship between Frequent and Complex Ventricular Ectopy during 24 h Ambulatory Electrocardiographic Monitoring
Abstract
Complex and frequent ventricular ectopy have been associated with an increased risk of sudden death in certain patient groups. To evaluate the relationship between complexity and frequency of ventricular ectopy, 275 consecutive 20- to 24-hour ambulatory electrocardiograms were analyzed. The unselected study population included 56% males and the average age was 56. Prior myocardial infarction was present in 28%. Dizziness, palpitations and syncope were present in 16, 30 and 13%, respectively. Complex ventricular ectopy (complexity) was defined as multiformity, bigeminy, couplets or salvos, ventricular tachycardia (VT), and R on T. Premature ventricular depolarizations (PVDs) were observed in 230 of 275 records and exhibited one or more criteria for complexity in 164 (71 %). Of the 164 records with complexity, 71 % had multiformity, 35% bigeminy, 32% couplets, 5% VT, and 22% R on T. Of 159 records with average PVD frequency ≤30/h, 98 (61%) exhibited complexity, whereas 66 of 71 (93%) records with > 30 PVD/h had complexity. Of 113 records with > 100 PVDs/24 h, 102 (90%) exhibited complexity, whereas 60 of 99 (61 %) records with between 2 and 100 PVDs on the entire record showed complexity. Of the 164 records with complexity, 43 had ‘rare PVDs’ ( < 30/24 h), but exhibited 72% multiformity, 5% bigeminy, 25% couplets, 2% VT, and 14% R on T. This study demonstrates a high prevalence (50–60%) of complexity in patients with ‘infrequent’ PVDs defined as < 30/24 h, < 30
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173268 Cardiology 1981;68:91–102Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.