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      Biograph Vision 600 PET performance testing and analysis


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          Objective To test and analyze the performance of Biograph Vision 600 PET/CT according to the NEMA NU2—2012 standard to achieve reliable, repeatable, and inter-system comparable performance measurement, and to provide a basis for future equipment stability testing and status detection.

          Methods The Biograph Vision PET equipment features a detector based on silicon photomultipliers, with 3.2 mm lutetium oxyorthosilicate crystals and full cover of the scintillation region. The spatial resolution, sensitivity, noise-equivalent count rate, scatter fraction, coincidence count rate, image quality, scatter correction, and time-of-flight resolution of Biograph Vision PET were tested by referring to the test model and method of the NEMA NU2—2012 standard.

          Results The Biograph Vision 600 PET equipment showed lateral and axial spatial resolutions of 3.69 mm and 3.81 mm at 1 cm off-center of the field of view, respectively and of 4.29 mm and 4.48 mm at 10 cm, respectively. The sensitivity was 17.5 kcps/MBq. The time-of-flight resolution changed from 210 ps to 215 ps as the count rate increased to the peak noise equivalent count rate. The NEMA peak noise-equivalent count rate was 247 kcps at 30.3 kBq/ml. The corresponding scatter fraction was 34.8%. With the NEMA module, the overall image quality contrast range was 73.6%-92.8%, and the background variability was 2.3%-6.5%; the mean lung residual error was 3.4%; and the time-of-flight resolution was 210 ps.

          Conclusion This performance test was performed according to the NEMA NU2—2012 standard, showing that all parameters were better than the ex-factory standard, which can provide a reference for other institutions selecting equipment and also provide a basis for future equipment stability testing and status detection.


          摘要: 目的 依据 NEMA NU2—2012 标准对 Biograph Vision 600 PET/CT 进行性能检测及研宄, 以实现可靠、可重复 和系统间可比较的性能测量, 为以后的设备稳定性检测及状态检测提供依据。 方法 Biograph Vision PET 设备采用基 于硅光电倍增管的探测器, 具有 3.2 mm 的硅酸镥晶体, 并全面覆盖闪烁体区域。参照 NEMA NU2—2012 标准的测试 模型和方法对 Biograph Vision PET 的空间分辨率、灵敏度、等效噪声计数率、散射分数、符合计数率、图像质量、散射 校正和飞行时间分辨率等性能参数进行测试。 结果 Biograph Vision 600 PET 视野中心 1 cm 处横向和轴向空间分辨 率分别为 3.69 mm 和 3.81 mm, 10 cm 处横向和轴向空间分辨率分别为 4.29 mm 和 4.48 mm, 灵敏度为 17.5 kcps/MBq, 随着计数率增加到峰值噪声等效计数率, 飞行时间分辨率从 210 ps 变化到 215 ps °在 30.3 kBq/mL 时 NEMA 峰值噪 声等效计数率为 247 kcps。对应的散射分数为 34.8%。使用 NEMA 模体得到的整体图像质量对比度范围为 73.6% ~ 92.8%, 背景变异系数范围为 2.3% ~ 6.5%; 平均肺插件残余误差为 3.4%; 飞行时间分辨率为 210 ps。 结论 本性能检 测根据 NEMA NU2—2012 标准完成, 各项参数均优于出厂标准, 为其他单位在设备选择时提供参考, 为以后的设备 稳定性检测及状态检测提供依据。

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          Author and article information

          Chinese Journal of Radiological Health
          Chinese Preventive Medical Association (Ji’an, China )
          01 December 2023
          01 April 2024
          : 32
          : 6
          : 668-672
          [1] 1Department of Nuclear Medicine, China-Japan Friendship Hospital, Beijing 100029 China
          [2] 2Department of radiology, Guang’anmen Hospital, Beijing 100053 China
          Author notes
          Corresponding author: LIU Jie, E-mail: 312220618@ 123456qq.com
          © 2023 Chinese Journal of Radiological Health

          This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

          Journal Article

          Medicine,Image processing,Radiology & Imaging,Bioinformatics & Computational biology,Health & Social care,Public health
          Positron emission computed tomography,Performance test,Time of flight,NEMA,Quality control


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