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      Polycystic Kidney of Infants and Children Morphology, Distribution and Relation of the Cysts

      Nephron

      S. Karger AG

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          Abstract

          (1) The results of 25 cases of renal cysts in pre- and post-natal infants, studied by microdissection, are reviewed here. (2) Cysts are designated as either corpuscular or tubular depending on the site of origin. One case was the single exception at there were both types of cyst present in approximately equal numbers. (3) Small corpuscular cysts are easily recognized by the presence of the glomerular tuft and/or attachment to the proximal convoluted tubule. In larger cysts the origin was established by position and the association with smaller cystic structures of recognizable type. (4) Definite, constantly occurring individual cystic patterns were observed in the tubular varieties, cysts being located at special sites in the nephron. (5) Cysts occurred in both complete and incomplete nephrons. (6) Various conclusions may be stated: (a) Microdissection shows that cysts vary greatly in form, their relation to other tissues (especially the tubules or renal corpuscles in which they arise) and in the stage of development of the individual, (b) The tubules are usually patent and various sizes of cyst and degree of change are found, indicating that not all the changes occurred at one time, (c) All the evidence suggests that in most, if not all, cystic change occurs in a formed nephron and is not due to embryological aberrations of the ‘non-union’ type.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1965
          1965
          25 November 2008
          : 2
          : 1
          : 15-31
          Affiliations
          Department of Pathology, University of Melbourne, Melbourne
          Article
          179371 Nephron 1965;2:15–31
          10.1159/000179371
          14333375
          © 1965 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 17
          Categories
          Paper

          Cardiovascular Medicine, Nephrology

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