+1 Recommend
1 collections
      Are you tired of sifting through news that doesn't interest you?
      Personalize your Karger newsletter today and get only the news that matters to you!

      Sign up

      • Record: found
      • Abstract: found
      • Article: found

      Infektiöse Keratitis nach cornealem Crosslinking: Geringes Risiko für schwerwiegenden Verlauf

      Karger Kompass Ophthalmologie
      S. Karger AG
      Cross-linking, Cornea, Keratoconus, Perforation, Infectious keratitis

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          Purpose: To describe a case of rapid keratitis and corneal perforation after epithelium off collagen cross-linking. Observations: We report a case of a 17-year-old male who underwent collagen cross-linking with the protocol and device approved by the United States Food and Drug Administration (FDA) that developed a corneal infiltrate 3 days after the procedure. He later developed corneal thinning and perforation on day 5 requiring the use of cyanoacrylate glue and a Kontur lens. Despite initial improvement in the infiltrate with fortified antibiotics he later had leakage of aqueous around the glue and a flat chamber requiring an emergent penetrating keratoplasty on postoperative day 16. Conclusion and importance: While collagen cross-linking has been very effective for treating keratoconus and is being recommended more frequently since FDA approval in the United States, severe complications such as corneal perforation requiring early transplant can still occur.

          Related collections

          Author and article information

          Karger Kompass Ophthalmologie
          S. Karger AG
          September 2020
          18 August 2020
          : 6
          : 3
          : 140-141
          Zentrum für Augenheilkunde, Uniklinik Köln, Köln, Deutschland
          Author notes
          *Prof. Dr. Björn Bachmann, Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Straße 62, 50931 Köln, Deutschland, bjoern.bachmann@uk-koeln.de
          510226 Kompass Ophthalmol 2020;6:140–141
          © 2020 S. Karger GmbH, Freiburg

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 2

          Vision sciences,Ophthalmology & Optometry,Pathology
          Cornea,Perforation,Keratoconus,Cross-linking,Infectious keratitis


          Comment on this article