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      Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

      , , ,
      Molecular and Cellular Biology
      American Society for Microbiology

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          Abstract

          Six monoclonal antibodies have been isolated from mice immunized with synthetic peptide immunogens whose sequences are derived from that of the human c-myc gene product. Five of these antibodies precipitate p62c-myc from human cells, and three of these five also recognize the mouse c-myc gene product. None of the antibodies sees the chicken p110gag-myc protein. All six antibodies recognize immunoblotted p62c-myc. These reagents also provide the basis for an immunoblotting assay by which to quantitate p62c-myc in cells.

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          Author and article information

          Journal
          Molecular and Cellular Biology
          Mol. Cell. Biol.
          American Society for Microbiology
          0270-7306
          1098-5549
          December 01 1985
          December 1985
          December 1985
          December 01 1985
          : 5
          : 12
          : 3610-3616
          Article
          10.1128/MCB.5.12.3610
          369192
          3915782
          feb729ee-eb45-4823-9e9a-0f2afa3b6bb0
          © 1985
          History

          Molecular medicine,Neurosciences
          Molecular medicine, Neurosciences

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