Contributors
Carina Conceicao: Role: Formal analysisRole: InvestigationRole: MethodologyRole: Project administrationRole:
Writing – original draftRole: Writing – review & editing
Nazia Thakur:
ORCID: https://orcid.org/0000-0002-4450-5911
Role: Formal analysisRole: InvestigationRole: MethodologyRole: Project administrationRole:
Writing – original draftRole: Writing – review & editing
Stacey Human:
ORCID: https://orcid.org/0000-0003-4735-2065
Role: Investigation
James T. Kelly:
ORCID: https://orcid.org/0000-0002-8307-507X
Role: Investigation
Leanne Logan: Role: Investigation
Dagmara Bialy: Role: Investigation
Sushant Bhat:
ORCID: https://orcid.org/0000-0003-1869-6176
Role: Investigation
Phoebe Stevenson-Leggett:
ORCID: https://orcid.org/0000-0002-6509-3354
Role: Investigation
Adrian K. Zagrajek: Role: Investigation
Philippa Hollinghurst: Role: Investigation
Michal Varga:
ORCID: https://orcid.org/0000-0002-7437-1723
Role: Investigation
Christina Tsirigoti: Role: Investigation
Matthew Tully:
ORCID: https://orcid.org/0000-0002-1395-1775
Role: Investigation
Chris Chiu: Role: Investigation
Katy Moffat:
ORCID: https://orcid.org/0000-0003-0120-7196
Role: Investigation
Adrian Paul Silesian:
ORCID: https://orcid.org/0000-0002-4100-9269
Role: Investigation
John A. Hammond:
ORCID: https://orcid.org/0000-0002-2213-3248
Role: InvestigationRole: MethodologyRole: Writing – review & editing
Helena J. Maier: Role: Conceptualization
Erica Bickerton:
ORCID: https://orcid.org/0000-0002-4012-1283
Role: ConceptualizationRole: Writing – review & editing
Holly Shelton: Role: Investigation
Isabelle Dietrich:
ORCID: https://orcid.org/0000-0002-6300-109X
Role: Investigation
Stephen C. Graham:
ORCID: https://orcid.org/0000-0003-4547-4034
Role: ConceptualizationRole: InvestigationRole: MethodologyRole: VisualizationRole:
Writing – review & editing
Dalan Bailey:
ORCID: https://orcid.org/0000-0002-5640-2266
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: SupervisionRole: VisualizationRole:
Writing – original draftRole: Writing – review & editing
Bill Sugden: Role: Academic Editor
Journal
Journal ID (nlm-ta): PLoS Biol
Journal ID (iso-abbrev): PLoS Biol
Journal ID (publisher-id): plos
Journal ID (pmc): plosbiol
Title:
PLoS Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1544-9173
ISSN
(Electronic):
1545-7885
Publication date
(Electronic):
21
December
2020
Publication date Collection:
December
2020
Publication date PMC-release: 21
December
2020
Volume: 18
Issue: 12
Electronic Location Identifier: e3001016
Affiliations
[1
]
The Pirbright Institute, Woking, Surrey, United Kingdom
[2
]
Department of Microbial Sciences, Faculty of Health and Medical Sciences, University
of Surrey, Guildford, United Kingdom
[3
]
Department of Pathology, University of Cambridge, Cambridge, United Kingdom
University of Wisconsin-Madison, UNITED STATES
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PBIOLOGY-D-20-02408
DOI: 10.1371/journal.pbio.3001016
PMC ID: 7751883
PubMed ID: 33347434
SO-VID: fec05da5-db68-4315-9c5a-3c85336db572
Copyright © © 2020 Conceicao et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 7
August
2020
Date
accepted
: 17
November
2020
Page count
Figures: 6,
Tables: 0,
Pages: 27
Funding
Funded by: funder-id http://dx.doi.org/10.13039/501100000265, Medical Research Council;
Award ID: MR/P021735/1
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5640-2266
Dalan Bailey
Funded by: funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/R019843/1
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5640-2266
Dalan Bailey
Funded by: funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/I/00007034
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5640-2266
Dalan Bailey
Funded by: funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/I/00007030
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5640-2266
Dalan Bailey
Funded by: funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/I/00007039
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5640-2266
Dalan Bailey
Funded by: funder-id http://dx.doi.org/10.13039/501100006041, Innovate UK;
Award ID: 971555
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5640-2266
Dalan Bailey
Funded by: funder-id http://dx.doi.org/10.13039/100004440, Wellcome Trust;
Award ID: 098406/Z/12/B
Award Recipient
:
ORCID: https://orcid.org/0000-0003-4547-4034
Stephen C. Graham
This work was supported by the following grants to DB: a UK Research and Innovation
(UKRI;
www.ukri.org) Medical Research Council (MRC) New Investigator Research Grant (MR/P021735/1), a
UKRI Biotechnology and Biological Sciences Research Council (BBSRC,
www.ukri.org) project grant (BB/R019843/1) and Institute Strategic Programme Grant (ISPG) to The
Pirbright Institute (BBS/E/I/00007034, BBS/E/I/00007030 and BBS/E/I/00007039) and
an Innovate UK Department for Health and Social Care project (SBRI Vaccines for Global
Epidemics – 795 Clinical; Contract 971555 ‘A Nipah vaccine to eliminate porcine reservoirs
and safeguard human health’). SCG is a Sir Henry Dale Fellow, jointly funded by the
Wellcome Trust and the Royal Society (098406/Z/12/B). The funders had no role in study
design, data collection and analysis, decision to publish, or preparation of the manuscript.
Categories
Subject:
Research Article
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
RNA viruses
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
SARS CoV 2
Subject:
Biology and life sciences
Subject:
Microbiology
Subject:
Medical microbiology
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Microbial pathogens
Subject:
Viral pathogens
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Coronaviruses
Subject:
SARS coronavirus
Subject:
SARS CoV 2
Subject:
Medicine and health sciences
Subject:
Pathology and laboratory medicine
Subject:
Pathogens
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
SARS CoV 2
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral pathogens
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
SARS CoV 2
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
RNA viruses
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
Biology and life sciences
Subject:
Microbiology
Subject:
Medical microbiology
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
Medicine and health sciences
Subject:
Pathology and laboratory medicine
Subject:
Pathogens
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral pathogens
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
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Mammals
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Bats
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Fruit Bats
Subject:
Biology and Life Sciences
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Zoology
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Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Bats
Subject:
Fruit Bats
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Bats
Subject:
Biology and Life Sciences
Subject:
Zoology
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Bats
Subject:
Biology and Life Sciences
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Cell Biology
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Cell Physiology
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Cell Fusion
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Biology and Life Sciences
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Molecular Biology
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Molecular Biology Techniques
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Transfection
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Research and Analysis Methods
Subject:
Molecular Biology Techniques
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Transfection
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Biology and Life Sciences
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Organisms
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Eukaryota
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Animals
Subject:
Vertebrates
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Amniotes
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Birds
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Fowl
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Gamefowl
Subject:
Chickens
Subject:
Biology and Life Sciences
Subject:
Zoology
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Animals
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Vertebrates
Subject:
Amniotes
Subject:
Birds
Subject:
Fowl
Subject:
Gamefowl
Subject:
Chickens
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Birds
Subject:
Poultry
Subject:
Chickens
Subject:
Biology and Life Sciences
Subject:
Zoology
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Birds
Subject:
Poultry
Subject:
Chickens
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Rodents
Subject:
Hamsters
Subject:
Biology and Life Sciences
Subject:
Zoology
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Rodents
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Hamsters
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